{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","value":"3"}]}],"title":"abdominal pain Grade 1"},{"categories":[{"measurements":[{"groupId":"OG000","value":"8"}]}],"title":"vaginal discharge Grade 1"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Toothache- Grade 1"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"vaginal fistula- Grade 2"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"vaginal pruritis- Grade 1"}],"denoms":[{"counts":[{"groupId":"OG000","value":"12"}],"units":"Participants"}],"description":"To investigate the safety of a 5-day course of self-administered intravaginal artesunate vaginal inserts (pessary) in women. Type, frequency, severity, and duration of reported and observed adverse events (AEs) using the U.S National Cancer Institute Common Terminology Criteria for Adverse Events, v5.0 (CTCAE 5.0) and the Division of AIDS Female Genital Adverse Events Grading Table will be submitted.","groups":[{"description":"Artesunate vaginal inserts/pessaries are used as a treatment for cervical precancerous lesions.\n\nArtesunate pessary: Subjects will use the study pessaries, placed in the vagina every day for 5 consecutive days.","id":"OG000","title":"Artesunate Vaginal Inserts/ Pessaries"}],"paramType":"COUNT_OF_PARTICIPANTS","reportingStatus":"POSTED","timeFrame":"Up to day 10 days","title":"Type, Frequency, Severity, and Duration of Adverse Events","type":"SECONDARY","unitOfMeasure":"Participants"}