{"denoms":[{"counts":[{"groupId":"OG000","value":"0"}],"units":"Participants"}],"description":"To determine the volume of distribution (V/F) of Artesunate (AS) following five consecutive days of self-administration of 200mg Artesunate vaginal inserts (pessaries) among healthy women.\n\nMean Artesunate volume of distribution (L/Kg) will be submitted.","groups":[{"description":"Artesunate vaginal inserts/pessaries are used as a treatment for cervical precancerous lesions.\n\nArtesunate pessary: Subjects will use the study pessaries, placed in the vagina every day for 5 consecutive days.","id":"OG000","title":"Artesunate Vaginal Inserts/ Pessaries"}],"populationDescription":"The plasma volume of distribution (V/F) of Artesunate (AS) could not be estimated because the concentration versus time profiles of both forms did not reach an elimination phase (i.e., the concentration versus time profile did not decrease) from 0 to 8h post administration of intravaginal artesunate.","reportingStatus":"POSTED","timeFrame":"Day 5","title":"To Determine the Volume of Distribution (V/F) of Artesunate (AS)","type":"SECONDARY"}