{"certainAgreement":{"piSponsorEmployee":true},"limitationsAndCaveats":{"description":"Pharmacokinetic (PK) sampling from 0 to 8 hours after intravaginal administration of artesunate was not sufficient to capture the elimination phase of the drug and its metabolite. As a result, key plasma pharmacokinetic parameters including apparent clearance (CL/F), apparent volume of distribution (Vd/F), elimination half-life (t½), and area under the concentration-time curve from time zero to infinity (AUC₀-∞) could not be estimated."},"pointOfContact":{"email":"kasorgi@email.unc.edu","organization":"UNC Lineberger Comprehensive Cancer Center","phone":"919-966-5280","title":"Sorgi Kate"}}