{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"17.72417","value":"83.2080"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"17"}],"units":"Participants"}],"title":"C1D4"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"15.16465","value":"83.3678"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"16"}],"units":"Participants"}],"title":"C1D11"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"15.67478","value":"85.0461"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"15"}],"units":"Participants"}],"title":"C1D18"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"14.57590","value":"93.4136"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"16"}],"units":"Participants"}],"title":"C2D1"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"14.94634","value":"83.4911"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"13"}],"units":"Participants"}],"title":"C2D4"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"17.53286","value":"81.6135"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"15"}],"units":"Participants"}],"title":"C2D11"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"16.14240","value":"85.1155"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"13"}],"units":"Participants"}],"title":"C2D18"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"12.80356","value":"87.1169"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"16"}],"units":"Participants"}],"title":"C3D1"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"17.87483","value":"82.8900"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"13"}],"units":"Participants"}],"title":"C3D4"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"15.56475","value":"90.0343"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"7"}],"units":"Participants"}],"title":"C4D1"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"13.74773","value":"90.0000"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"5"}],"units":"Participants"}],"title":"C5D1"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"14.84924","value":"69.5000"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"2"}],"units":"Participants"}],"title":"C6D1"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"18.00761","value":"87.1937"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"17"}],"units":"Participants"}],"title":"End of treatment"}],"denoms":[{"counts":[{"groupId":"OG000","value":"17"}],"units":"Participants"}],"description":"eGFR creatinine was evaluated using Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula. Absolute values in eGFR was presented. Here, mL/min/1.73 m\\^2 is defined as milliliters per minute per 1.73 square meters.","dispersionType":"Standard Deviation","groups":[{"description":"Participants received 3 cycles of oral solution of Xevinapant at a dose of 200 milligrams per day (mg/day) once daily from Day 1 to 14, per 3-week cycle. The first three cycles are given in combination with Cisplatin at dose of 40 milligrams per square meter (mg/m2) once daily on Cycle 1 Day 2 (C1D2, C1D9, C1D16, C2D2, C2D9, C2D16, and C3D2) With 70 Gray (Gy) of intensity modulated radiation therapy (IMRT) in 35 fractions, 2 Gy/fraction, 5 days/week followed by 3 cycles of monotherapy of Xevinapant at a dose of 200 mg/day from Day 1 to 14, per 3-week cycle (Each cycle is of 3 weeks).","id":"OG000","title":"Sequence 1"}],"paramType":"MEAN","populationDescription":"SAS included all participants who were administered any dose of any study intervention. Here\" overall number of participants analyzed signified\" participants who were evaluable for this outcome measure and \"number analyzed\" signifies participants who were evaluable at specified timepoints.","reportingStatus":"POSTED","timeFrame":"At Cycle1 Day 4 (C1D4), C1D11, C1D18, C2D1, C2D4, C2D11, C2D18, C3D1, C3D4, C4D1, C5D1, C6D1 and End of treatment (Day 134) (each cycle is of 3 weeks)","title":"Absolute Estimated Glomerular Filtration Rate (eGFR) Values","type":"SECONDARY","unitOfMeasure":"mL/min/1.73 m^2"}