{"denomUnitsSelected":"Participants","description":"DOR was defined as the time from the date of first documentation of confirmed PR or better (sCR+ CR+ VGPR+ PR) to the date of first documentation of PD or death due to any cause. PR: \\>=50% reduction of serum M-protein and \\>=90% reduction in urine M-protein or \\<200 mg/24 hour, or \\>=50% decrease in uninvolved FLC or \\>=50% reduction in plasma cells. At baseline, a \\>=50% decrease in size of soft tissue plasmacytomas is required. PD: increase of \\>=25% from lowest response value in any one or more of the following: serum M-component increase \\>=0.5 g/dL or urine M-component increase \\>=200 mg/24-hour; difference between involved and uninvolved FLC levels increase must be \\>10 mg/dL; bone marrow plasma cell \\>=10%; definite development of new bone lesions or soft tissue plasmacytomas or definite increase in the size of existing bone lesions or soft tissue plasmacytomas; development of hypercalcemia that can be attributed solely to plasma cell proliferative disorder.","reportingStatus":"NOT_POSTED","timeFrame":"Up to 16.7 months","title":"Duration of Response (DOR)","type":"SECONDARY"}