{"calculatePct":false,"classes":[{"categories":[{"measurements":[{"groupId":"OG000","value":"2"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"4"}],"units":"Participants"}],"description":"OR: CR (complete metabolic response (CMR)+complete radiological response (CRR))+PR (partial MR response (PMR)+partial RR(PRR)). CMR: score 1(no uptake above background)/2(uptake≤mediastinum)/3(uptake \\>mediastinum but ≤liver)with/without a residual mass on positron emission tomography 5-point scale;no new lesions,CRR:target nodes/nodal masses regressed to ≤1.5 cm in longest transverse diameter of lesion (LDi);no extralymphatic sites of disease;absent non-measured lesion(NMLs);organ enlargement regress to normal; no new sites;bone marrow normal by morphology. PMR:score 4(uptake moderately\\>liver)/5(uptake markedly\\>liver, new lesions) with reduced uptake compared with baseline and residual mass;no new lesions;responding disease at interim/residual disease at end of treatment. PRR:≥50% decrease in sum of product of diameters up to 6 target nodes and extra-nodal sites;absent/ normal,regressed,but no increase of NMLs;spleen regressed by\\>50% in length beyond normal.","groups":[{"description":"Participants with Relapsed/Refractory Richter Transformation received the following treatment during the study:Lymphodepletion chemotherapy regimen of fludarabine 30 mg/m\\^2/day IV and cyclophosphamide 500 mg/m\\^2/day IV for 3 days (Day -5 to Day -3). A single IV infusion of brexucabtagene autoleucel at target dose of 2 × 10\\^6 anti-CD19 CAR T cells/kg on Day 0.","id":"OG000","title":"Substudy B (Relapsed/Refractory Richter Transformation): Brexucabtagene Autoleucel"}],"paramType":"COUNT_OF_PARTICIPANTS","populationDescription":"Participants in substudy B, in the Modified Intent-to-Treat Analysis Set were analyzed.","reportingStatus":"POSTED","timeFrame":"Up to 2 years","title":"Substudy B: Number of Participants With OR Determined by Investigator Assessment Per the Lugano Classification","type":"SECONDARY","unitOfMeasure":"Participants"}