{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","value":"-90.5"},{"groupId":"OG001","lowerLimit":"-100","upperLimit":"-91.1","value":"-96.7"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"1"},{"groupId":"OG001","value":"7"},{"groupId":"OG002","value":"0"}],"units":"Participants"}],"description":"Assessed by comparing each participant's highest post-dose TCR-T cell count (copies per 1×10⁶ cells by qPCR) to the TCR-T cell count at Day 28. Percent change was calculated as: ((Day 28 - peak post-dose) / peak post-dose) × 100.","dispersionType":"Full Range","groups":[{"description":"Participants received a single intravenous infusion of autologous TCR-T cells manufactured at Dose Level 1 (target 5 (1 to \\<10) × 10⁹ TCR+ cells) following apheresis and manufacturing per protocol. This represents the lowest dose cohort in the sequential dose-escalation design.","id":"OG000","title":"Assigned Dose Level 1 (Target 5 × 10⁹ TCR+ Cells)"},{"description":"Participants received a single intravenous infusion of autologous TCR-T cells manufactured at Dose Level 2 (target 40 (10 to \\<70) × 10⁹ TCR+ cells) following apheresis and manufacturing per protocol. This represents the intermediate dose cohort in the sequential dose-escalation design.","id":"OG001","title":"Assigned Dose Level 2 (Target 40 × 10⁹ TCR+ Cells)"},{"description":"Participants received a single intravenous infusion of autologous TCR-T cells manufactured at Dose Level 3 (target 100 (70 to 100) × 10⁹ TCR+ cells) following apheresis and manufacturing per protocol. This represents the highest dose cohort in the sequential dose-escalation design.","id":"OG002","title":"Assigned Dose Level 3 (Target 100 × 10⁹ TCR+ Cells)"}],"paramType":"MEDIAN","populationDescription":"8 participants received TCR-T infusion and were included in the analysis (1 assigned at Dose Level 1, 7 assigned at Dose Level 2).","reportingStatus":"POSTED","timeFrame":"Post-dose through Day 28","title":"Percent Change in TCR-T Cell Count From Post Dose to Day 28","type":"SECONDARY","unitOfMeasure":"percent change from peak post dose"}