{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"51.1","value":"35.80"},{"groupId":"OG002","spread":"54.3","value":"24.20"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"18"},{"groupId":"OG001","value":"0"},{"groupId":"OG002","value":"9"}],"units":"Participants"}],"title":"Cycle 1 week 1 day 1"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"51.3","value":"39.25"},{"comment":"Here, \"NA\" indicates that data could not be evaluated due to smaller number of participants.","groupId":"OG001","spread":"NA","value":"NA"},{"groupId":"OG002","spread":"36.9","value":"33.20"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"17"},{"groupId":"OG001","value":"1"},{"groupId":"OG002","value":"9"}],"units":"Participants"}],"title":"Cycle 1 week 2 day 1"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"27.8","value":"50.32"},{"comment":"Here, \"NA\" indicates that data could not be evaluated due to smaller number of participants.","groupId":"OG001","spread":"NA","value":"NA"},{"groupId":"OG002","spread":"66.3","value":"37.99"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"18"},{"groupId":"OG001","value":"1"},{"groupId":"OG002","value":"11"}],"units":"Participants"}],"title":"Cycle 1 week 3 day 1"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"36.8","value":"55.93"},{"groupId":"OG002","spread":"54.6","value":"37.29"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"14"},{"groupId":"OG001","value":"0"},{"groupId":"OG002","value":"7"}],"units":"Participants"}],"title":"Cycle 2 day 1"}],"denoms":[{"counts":[{"groupId":"OG000","value":"18"},{"groupId":"OG001","value":"1"},{"groupId":"OG002","value":"11"}],"units":"Participants"}],"description":"The plasma PK of AZD4573 when administered in participants was assessed.","dispersionType":"Geometric Coefficient of Variation","groups":[{"description":"Participants with non-NK PTCL received 12 mg dose of AZD4573 once weekly until disease progression.","id":"OG000","title":"Cohort 1 Non-NK PTCL"},{"description":"Participants with NK PTCL received 12 mg dose of AZD4573 once weekly until disease progression.","id":"OG001","title":"Cohort 2 NK PTCL"},{"description":"Participants with cHL received 12 mg dose of AZD4573 once weekly until disease progression.","id":"OG002","title":"Cohort 3 cHL"}],"paramType":"GEOMETRIC_MEAN","populationDescription":"PK set included all participants who received any amount of study intervention with at least 1 reportable concentration. Here, 'n\" (number analyzed in each row) signifies the participants with available data that were analyzed for each timepoint of this outcome measure.","reportingStatus":"POSTED","timeFrame":"Cycle 1 (Cycle length is 35 days), Day 1 of Weeks 1-3 and Cycle 2 (Cycle length is 21 Days), Day 1.","title":"Volume of Distribution at Steady State (Vss)","type":"SECONDARY","unitOfMeasure":"Liter"}