{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"0.97","upperLimit":"6.00","value":"2.000"},{"comment":"Here, \"NA\" indicates that data could not be evaluated due to smaller number of participants.","groupId":"OG001","lowerLimit":"1.90","upperLimit":"2.15","value":"NA"},{"groupId":"OG002","lowerLimit":"1.00","upperLimit":"23.00","value":"2.083"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"31"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"19"}],"units":"Participants"}],"title":"Cycle 1 week 1 day 1"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"1.87","upperLimit":"6.08","value":"2.083"},{"comment":"Here, \"NA\" indicates that data could not be evaluated due to smaller number of participants.","groupId":"OG001","lowerLimit":"2.15","upperLimit":"2.15","value":"NA"},{"groupId":"OG002","lowerLimit":"1.87","upperLimit":"6.00","value":"2.083"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"25"},{"groupId":"OG001","value":"1"},{"groupId":"OG002","value":"15"}],"units":"Participants"}],"title":"Cycle 1 week 2 day 1"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"0.87","upperLimit":"6.00","value":"2.083"},{"comment":"Here, \"NA\" indicates that data could not be evaluated due to smaller number of participants.","groupId":"OG001","lowerLimit":"2.25","upperLimit":"2.25","value":"NA"},{"groupId":"OG002","lowerLimit":"1.78","upperLimit":"4.00","value":"2.133"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"25"},{"groupId":"OG001","value":"1"},{"groupId":"OG002","value":"16"}],"units":"Participants"}],"title":"Cycle 1 week 3 day 1"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"1.00","upperLimit":"3.58","value":"2.133"},{"groupId":"OG002","lowerLimit":"0.97","upperLimit":"5.02","value":"2.083"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"16"},{"groupId":"OG001","value":"0"},{"groupId":"OG002","value":"14"}],"units":"Participants"}],"title":"Cycle 2 day 1"}],"denoms":[{"counts":[{"groupId":"OG000","value":"31"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"19"}],"units":"Participants"}],"description":"The plasma PK of AZD4573 when administered in participants was assessed.","dispersionType":"Full Range","groups":[{"description":"Participants with non-NK PTCL received 12 mg dose of AZD4573 once weekly until disease progression.","id":"OG000","title":"Cohort 1 Non-NK PTCL"},{"description":"Participants with NK PTCL received 12 mg dose of AZD4573 once weekly until disease progression.","id":"OG001","title":"Cohort 2 NK PTCL"},{"description":"Participants with cHL received 12 mg dose of AZD4573 once weekly until disease progression.","id":"OG002","title":"Cohort 3 cHL"}],"paramType":"MEDIAN","populationDescription":"PK set included all participants who received any amount of study intervention with at least 1 reportable concentration. Here, 'n\" (number analyzed in each row) signifies the participants with available data that were analyzed for each timepoint of this outcome measure.","reportingStatus":"POSTED","timeFrame":"Cycle 1 (Cycle length is 35 days), Day 1 of Weeks 1-3 and Cycle 2 (Cycle length is 21 Days), Day 1.","title":"Time to Reach Peak Observed Concentration Following Drug Administration (Tmax)","type":"SECONDARY","unitOfMeasure":"Hour"}