{"groups":[{"description":"SBT6050 plus trastuzumab deruxtecan\n\nSBT6050: Dose range of 0.45 to 0.6 mg/kg by subcutaneous (SC) injection in 21-day cycles\n\ntrastuzumab deruxtecan: 5.4 mg/kg by intravenous (IV) infusion in 21-day cycles","id":"FG000","title":"SBT6050 + T-DXd (5.4 mg/kg)"},{"description":"SBT6050 plus trastuzumab deruxtecan\n\nSBT6050: Dosed with 0.45 mg/kg by subcutaneous (SC) injection in 21-day cycles\n\ntrastuzumab deruxtecan: 6.4 mg/kg by IV infusion in 21-day cycles","id":"FG001","title":"SBT6050 + T-DXd (6.4 mg/kg)"},{"description":"SBT6050 plus tucatinib, trastuzumab, and capecitabine\n\nSBT6050: Dose range of 0.45 to 0.6 mg/kg by subcutaneous (SC) injection in 21-day cycles\n\ntucatinib: 300 mg by mouth (PO) twice daily (BID)\n\ntrastuzumab: 8 mg/kg loading dose (first dose), then 6 mg/kg maintenance dose (subsequent doses) IV infusion in 21-day cycles\n\ncapecitabine: 1000 mg/m2 PO BID for 14 days of each 21-day cycle","id":"FG002","title":"SBT6050 + Tucatinib + Trastuzumab + Capecitabine"},{"description":"SBT6050 plus tucatinib and trastuzumab\n\nSBT6050: Dosed with 0.45 mg/kg by subcutaneous (SC) injection in 21-day cycles\n\ntucatinib: 300 mg by mouth (PO) twice daily (BID)\n\ntrastuzumab: 8 mg/kg loading dose (first dose), then 6 mg/kg maintenance dose (subsequent doses) IV infusion in 21-day cycles","id":"FG003","title":"SBT6050 + Tucatinib + Trastuzumab"}],"periods":[{"dropWithdraws":[{"reasons":[{"groupId":"FG000","numSubjects":"0"},{"groupId":"FG001","numSubjects":"1"},{"groupId":"FG002","numSubjects":"0"},{"groupId":"FG003","numSubjects":"1"}],"type":"Study Termination by Sponsor"}],"milestones":[{"achievements":[{"groupId":"FG000","numSubjects":"0"},{"groupId":"FG001","numSubjects":"1"},{"groupId":"FG002","numSubjects":"0"},{"groupId":"FG003","numSubjects":"1"}],"type":"STARTED"},{"achievements":[{"groupId":"FG000","numSubjects":"0"},{"groupId":"FG001","numSubjects":"0"},{"groupId":"FG002","numSubjects":"0"},{"groupId":"FG003","numSubjects":"0"}],"type":"COMPLETED"},{"achievements":[{"groupId":"FG000","numSubjects":"0"},{"groupId":"FG001","numSubjects":"1"},{"groupId":"FG002","numSubjects":"0"},{"groupId":"FG003","numSubjects":"1"}],"type":"NOT COMPLETED"}],"title":"Overall Study"}]}