{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","value":"25"}],"title":"Grade 1"},{"measurements":[{"groupId":"OG000","value":"5"}],"title":"Grade 2"},{"measurements":[{"groupId":"OG000","value":"0"}],"title":"Grade 3"},{"measurements":[{"groupId":"OG000","value":"0"}],"title":"Grade 4"},{"measurements":[{"groupId":"OG000","value":"0"}],"title":"Grade 5"},{"measurements":[{"groupId":"OG000","value":"8"}],"title":"No CRS"}],"title":"Day 4"},{"categories":[{"measurements":[{"groupId":"OG000","value":"8"}],"title":"Grade 1"},{"measurements":[{"groupId":"OG000","value":"1"}],"title":"Grade 2"},{"measurements":[{"groupId":"OG000","value":"0"}],"title":"Grade 3"},{"measurements":[{"groupId":"OG000","value":"0"}],"title":"Grade 4"},{"measurements":[{"groupId":"OG000","value":"0"}],"title":"Grade 5"},{"measurements":[{"groupId":"OG000","value":"29"}],"title":"No CRS"}],"title":"Day 7"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}],"title":"Grade 1"},{"measurements":[{"groupId":"OG000","value":"0"}],"title":"Grade 2"},{"measurements":[{"groupId":"OG000","value":"0"}],"title":"Grade 3"},{"measurements":[{"groupId":"OG000","value":"0"}],"title":"Grade 4"},{"measurements":[{"groupId":"OG000","value":"0"}],"title":"Grade 5"},{"measurements":[{"groupId":"OG000","value":"38"}],"title":"No CRS"}],"title":"Day 10"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}],"title":"Grade 1"},{"measurements":[{"groupId":"OG000","value":"0"}],"title":"Grade 2"},{"measurements":[{"groupId":"OG000","value":"0"}],"title":"Grade 3"},{"measurements":[{"groupId":"OG000","value":"0"}],"title":"Grade 4"},{"measurements":[{"groupId":"OG000","value":"0"}],"title":"Grade 5"},{"measurements":[{"groupId":"OG000","value":"38"}],"title":"No CRS"}],"title":"Day 14"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}],"title":"Grade 1"},{"measurements":[{"groupId":"OG000","value":"0"}],"title":"Grade 2"},{"measurements":[{"groupId":"OG000","value":"0"}],"title":"Grade 3"},{"measurements":[{"groupId":"OG000","value":"0"}],"title":"Grade 4"},{"measurements":[{"groupId":"OG000","value":"0"}],"title":"Grade 5"},{"measurements":[{"groupId":"OG000","value":"38"}],"title":"No CRS"}],"title":"Day 21"}],"denoms":[{"counts":[{"groupId":"OG000","value":"38"}],"units":"Participants"}],"description":"Overall incidence of CRS of any grade and grade 3 or 4 CRS post CAR T-cell infusion will be reported on all patients.","groups":[{"description":"Patients complete apheresis and proceed to lymphodepleting chemotherapy with cyclophosphamide 300mg/m\\^2 and fludarabine 30mg/m\\^2 for 3 consecutive days followed by the infusion of BCMA CAR T-cells at a target dose of 450 x10\\^6 cells. Maintenance lenalidomide, starting at 5mg a day for 21 days of a 28-day cycle will be initiated at a minimum of at least 30 days, but no later than 180 days after the CAR T-cell infusion and will continue until the patient reaches 12 months post CAR T-cell infusion and continue free of progression.\n\nLenalidomide: Maintenance lenalidomide, starting at 5 mg a day for 21 days of a 28-day cycle, will be initiated at a minimum of at least 30 days, but no later than 180 days after the CAR T-cell infusion and will continue until the participant reaches 12 months post CAR T-cell infusion and continues free of progression\n\nbb2121: Participants receive infusion of BCMA CAR T-cells at a target dose of 450 x 10\\^6 cells.\n\nCyclophosphamide: 300 mg/m\\^2/day for 3 consecutive days prior to the CAR T infusion\n\nFludarabine: 30 mg/m\\^2/day or 3 consecutive days prior to the CAR T infusion\n\nleukapheresis: Placement of central line catheter and leukapheresis","id":"OG000","title":"Lenalidomide and bb2121"}],"paramType":"COUNT_OF_PARTICIPANTS","populationDescription":"Participants who received an infusion","reportingStatus":"POSTED","timeFrame":"Day 4, Day 7, Day 10, Day 14, and Day 21 post-infusion","title":"Incidence of Cytokine Release Syndrome (CRS)","type":"SECONDARY","unitOfMeasure":"Participants"}