{"analyses":[{"ciLowerLimit":"-2.38","ciNumSides":"TWO_SIDED","ciPctValue":"90","ciUpperLimit":"1.18","dispersionType":"STANDARD_ERROR_OF_MEAN","dispersionValue":"1.01","estimateComment":"Week 4","groupIds":["OG000","OG001"],"nonInferiorityType":"SUPERIORITY","paramType":"Mean Difference (Final Values)","paramValue":"-0.60"}],"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"1.01","upperLimit":"3.88","value":"2.45"},{"groupId":"OG001","lowerLimit":"0.79","upperLimit":"2.90","value":"1.84"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"5"},{"groupId":"OG001","value":"9"}],"units":"Participants"}],"description":"The Cancer-Related Cachexia Symptom Assessment-Appetite was a self-reported questionnaire that measured the severity of anorexia. The measure consisted of 1 question that asked study participants to rate their appetite over the past 7 days from 0-\"no appetite\" to 10-\"very good appetite\", where higher score indicated better appetite.\n\nIn this Outcome Measure (OM), changes from baseline in the Cancer-Related Cachexia Symptom Assessment-Appetite score at Week 4 were summarized descriptively by treatment group.","dispersionType":"90% Confidence Interval","groups":[{"description":"Participants received placebo during the 6-week double-blind phase (Part A) Q3W SC.","id":"OG000","title":"Placebo"},{"description":"Participants received PF-06946860 200 mg during the 6-week double-blind phase (Part A) Q3W SC.","id":"OG001","title":"PF-06946860 200mg Q3W"}],"paramType":"LEAST_SQUARES_MEAN","populationDescription":"The analysis set included all participants randomly assigned to study intervention and who took at least 1 dose of study intervention. The number analyzed in each group was the number of participants with non-missing data in the analysis set at a given visit. Number of participants analyzed/number analyzed = number of participants evaluable for this OM in each treatment group.","reportingStatus":"POSTED","timeFrame":"Baseline, Week 4","title":"Change From Baseline in Cancer-Related Cachexia Symptom Assessment in Appetite Score at Week 4 in Part A","type":"PRIMARY","unitOfMeasure":"Units on a Scale"}