{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"Alanine aminotransferase increased"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"Alkaline phosphatase increased"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"Aspartate aminotransferase increased"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"Blood bilirubin increased"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"Creatinine increased"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"Hypercalcemia"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"Hyperkalemia"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"Hypermagnesemia"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"Hypernatremia"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"Hypoalbuminemia"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"Hypocalcemia"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"Hypoglycemia"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Hypokalemia"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"Hypomagnesemia"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"Hyponatremia"}],"denoms":[{"counts":[{"groupId":"OG000","value":"4"}],"units":"Participants"}],"description":"Chemistry parameters that were assessed included: Alanine aminotransferase increased, Alkaline phosphatase increased, Aspartate aminotransferase increased, Blood bilirubin increased, Creatinine increased, Hypercalcemia, Hyperkalemia, Hypermagnesemia, Hypernatremia, Hypoalbuminemia, Hypocalcemia, Hypoglycemia, Hypokalemia, Hypomagnesemia, Hyponatremia. Abnormalities were graded based on CTCAE version 5.0- Grade 1: mild; Grade 2: moderate; Grade 3: severe or clinically significant; Grade 4: life-threatening.","groups":[{"description":"Participants received an initial priming dose of 600 microgram per kilogram elranatamab subcutaneously on Cycle 0 Day 1 (7 days prior to Cycle 1 Day 1). During treatment cycle, participants were administered 1000 microgram per kilogram elranatamab weekly during each cycle (each cycle was of 3 weeks).","id":"OG000","title":"Elranatamab"}],"paramType":"COUNT_OF_PARTICIPANTS","populationDescription":"SAS included all enrolled participants who received at least 1 dose of study intervention.","reportingStatus":"POSTED","timeFrame":"From first dose of study intervention and up to 90 days after last dose or start of new anticancer therapy (maximum of 65.1 weeks of treatment)","title":"Number of Participants With Shift From Grade Less Than or Equal to (<=) 2 at Baseline to Grade 3 or 4 Post -Baseline in Chemistry Parameters by NCI CTCAE v 5.0","type":"SECONDARY","unitOfMeasure":"Participants"}