{"description":"Analysis was performed on safety set population which included all participants who took at least one dose of FTD/TPI and were analyzed according to the treatment actually received. Reported serious AEs and other AEs were treatment-emergent AEs that developed, worsened or became serious from baseline (Cycle 1 Day 1) up to 30 days after the last dose of the study drug.","eventGroups":[{"deathsNumAffected":208,"deathsNumAtRisk":246,"description":"Participants were administered 35 mg/m²/dose FTD/TPI orally BID, within 1 hour after completion of morning and evening meals, 5 days on (Day 1 to 5 and Day 8 to 12) with 2 days off (Day 6 to 7 and Day 13 to 14), over 2 weeks, followed by a 14-day rest; with bevacizumab 5 mg/kg, IV infusion administered every 2 weeks (Day 1 and Day 15). This treatment cycle was repeated every 4 weeks.","id":"EG000","otherNumAffected":241,"otherNumAtRisk":246,"seriousNumAffected":66,"seriousNumAtRisk":246,"title":"Trifluridine/Tipiracil + Bevacizumab"},{"deathsNumAffected":224,"deathsNumAtRisk":246,"description":"Participants were administered 35 mg/m²/dose of FTD/TPI orally BID, within 1 hour after completion of morning and evening meals, 5 days on (Day 1 to 5 and Day 8 to 12) with 2 days off (Day 6 to 7 and Day 13 to 14), over 2 weeks, followed by a 14-day rest. This treatment cycle was repeated every 4 weeks.","id":"EG001","otherNumAffected":241,"otherNumAtRisk":246,"seriousNumAffected":79,"seriousNumAtRisk":246,"title":"Trifluridine/Tipiracil"}],"frequencyThreshold":"5","otherEvents":[{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Investigations","sourceVocabulary":"MedDRA (25.0)","stats":[{"groupId":"EG000","numAffected":34,"numAtRisk":246},{"groupId":"EG001","numAffected":18,"numAtRisk":246}],"term":"Neutrophil count decreased"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Investigations","sourceVocabulary":"MedDRA (25.0)","stats":[{"groupId":"EG000","numAffected":24,"numAtRisk":246},{"groupId":"EG001","numAffected":6,"numAtRisk":246}],"term":"Platelet count decreased"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Investigations","sourceVocabulary":"MedDRA (25.0)","stats":[{"groupId":"EG000","numAffected":20,"numAtRisk":246},{"groupId":"EG001","numAffected":14,"numAtRisk":246}],"term":"Alanine 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lymphatic system disorders","sourceVocabulary":"MedDRA (25.0)","stats":[{"groupId":"EG000","numAffected":44,"numAtRisk":246},{"groupId":"EG001","numAffected":29,"numAtRisk":246}],"term":"Thrombocytopenia"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Blood and lymphatic system disorders","sourceVocabulary":"MedDRA (25.0)","stats":[{"groupId":"EG000","numAffected":19,"numAtRisk":246},{"groupId":"EG001","numAffected":21,"numAtRisk":246}],"term":"Leukopenia"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"General disorders","sourceVocabulary":"MedDRA (25.0)","stats":[{"groupId":"EG000","numAffected":61,"numAtRisk":246},{"groupId":"EG001","numAffected":58,"numAtRisk":246}],"term":"Asthenia"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"General disorders","sourceVocabulary":"MedDRA 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(25.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":246},{"groupId":"EG001","numAffected":1,"numAtRisk":246}],"term":"Cancer pain"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Neoplasms benign, malignant and unspecified (incl cysts and polyps)","sourceVocabulary":"MedDRA (25.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":246},{"groupId":"EG001","numAffected":1,"numAtRisk":246}],"term":"Malignant pleural effusion"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Neoplasms benign, malignant and unspecified (incl cysts and polyps)","sourceVocabulary":"MedDRA (25.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":246},{"groupId":"EG001","numAffected":1,"numAtRisk":246}],"term":"Metastases to ovary"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Vascular disorders","sourceVocabulary":"MedDRA (25.0)","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":246},{"groupId":"EG001","numAffected":1,"numAtRisk":246}],"term":"Deep 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