{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"1.00","upperLimit":"1.00","value":"1.00"},{"groupId":"OG001","lowerLimit":"1.00","upperLimit":"3.00","value":"1.00"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"25"},{"groupId":"OG001","value":"24"}],"units":"Participants"}],"title":"Mouth or throat sore interference - Day -3"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"1.00","upperLimit":"4.00","value":"1.00"},{"groupId":"OG001","lowerLimit":"1.00","upperLimit":"5.00","value":"1.00"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"25"},{"groupId":"OG001","value":"22"}],"units":"Participants"}],"title":"Mouth or throat sore interference - Day 8"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"1.00","upperLimit":"1.00","value":"1.00"},{"groupId":"OG001","lowerLimit":"1.00","upperLimit":"5.00","value":"1.00"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"23"},{"groupId":"OG001","value":"22"}],"units":"Participants"}],"title":"Mouth or throat sore interference - date of discharge or Day 14 (whichever is sooner)"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"1.00","upperLimit":"3.00","value":"1.00"},{"groupId":"OG001","lowerLimit":"1.00","upperLimit":"3.00","value":"1.00"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"25"},{"groupId":"OG001","value":"24"}],"units":"Participants"}],"title":"Decreased appetite interference - Day -3"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"1.00","upperLimit":"5.00","value":"3.00"},{"groupId":"OG001","lowerLimit":"1.00","upperLimit":"5.00","value":"3.50"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"25"},{"groupId":"OG001","value":"22"}],"units":"Participants"}],"title":"Decreased appetite interference - Day 8"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"1.00","upperLimit":"5.00","value":"2.00"},{"groupId":"OG001","lowerLimit":"1.00","upperLimit":"5.00","value":"3.00"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"23"},{"groupId":"OG001","value":"22"}],"units":"Participants"}],"title":"Decreased appetite interference - date of discharge or Day 14 (whichever is sooner)"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"1.00","upperLimit":"3.00","value":"1.00"},{"groupId":"OG001","lowerLimit":"1.00","upperLimit":"2.00","value":"1.00"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"25"},{"groupId":"OG001","value":"24"}],"units":"Participants"}],"title":"Abdominal pain interference - Day -3"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"1.00","upperLimit":"4.00","value":"2.00"},{"groupId":"OG001","lowerLimit":"1.00","upperLimit":"4.00","value":"1.50"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"25"},{"groupId":"OG001","value":"22"}],"units":"Participants"}],"title":"Abdominal pain interference - Day 8"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"1.00","upperLimit":"4.00","value":"1.00"},{"groupId":"OG001","lowerLimit":"1.00","upperLimit":"4.00","value":"1.00"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"23"},{"groupId":"OG001","value":"22"}],"units":"Participants"}],"title":"Abdominal pain interference - date of discharge or Day 14 (whichever is sooner)"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"1.00","upperLimit":"3.00","value":"1.00"},{"groupId":"OG001","lowerLimit":"1.00","upperLimit":"2.00","value":"1.00"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"24"},{"groupId":"OG001","value":"24"}],"units":"Participants"}],"title":"Bowel incontinence interference - Day -3"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"1.00","upperLimit":"5.00","value":"1.00"},{"groupId":"OG001","lowerLimit":"1.00","upperLimit":"4.00","value":"1.00"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"25"},{"groupId":"OG001","value":"22"}],"units":"Participants"}],"title":"Bowel incontinence interference - Day 8"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"1.00","upperLimit":"5.00","value":"2.00"},{"groupId":"OG001","lowerLimit":"1.00","upperLimit":"5.00","value":"1.00"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"23"},{"groupId":"OG001","value":"22"}],"units":"Participants"}],"title":"Bowel incontinence interference - date of discharge or Day 14 (whichever is sooner)"}],"denoms":[{"counts":[{"groupId":"OG000","value":"25"},{"groupId":"OG001","value":"24"}],"units":"Participants"}],"description":"* Questions regarding gastrointestinal, pain, and psychological symptoms interfering with daily activities\n* Responses are scored from 1-5 with 1=not at all to 5=very much","dispersionType":"Full Range","groups":[{"description":"Patients will receive six doses of Uproleselan intravenously. The doses will begin the evening of Day -3 and continue every 12 hours through the morning of Day 0, prior to hematopoietic stem cell transplant (auto-HCT). On the evening of Day -2, patients also receive one dose of standard of care Melphalan intravenously.","id":"OG000","title":"Uproleselan + Standard of Care Melphalan"},{"description":"Patients will receive six doses of placebo intravenously. The doses will begin the evening of Day -3 and continue every 12 hours through the morning of Day 0, prior to hematopoietic stem cell transplant (auto-HCT). On the evening of Day -2, patients also receive one dose of standard of care Melphalan intravenously.","id":"OG001","title":"Placebo + Standard of Care Melphalan"}],"paramType":"MEDIAN","populationDescription":"The number of participants analyzed at each time point may differ from the overall number of participants analyzed because the data was not collected. One patient in the placebo + standard of care melphalan arm was not evaluable for the outcome measure.","reportingStatus":"POSTED","timeFrame":"Day -3, Day +8, date of discharge or Day +14 (whichever is sooner) (up to 18 days)","title":"Median Change in Scores of Quality of Life as Measured by the CTCAE Pro Form v 1.0","type":"SECONDARY","unitOfMeasure":"score on a scale"}