{"anticipatedPostingDate":"2027-12","denomUnitsSelected":"Participants","description":"The following hematology and coagulation parameters were assessed: activated partial thromboplastin time prolonged, anemia, hemoglobin increased, INR increased, leukocytosis, neutrophil count decreased, platelet count decreased, and white blood cell decreased. Laboratory abnormalities were graded according to NCI CTCAE v4.03 where grade 1= mild, grade 2= moderate, grade 3= severe, grade 4= life-threatening event due to AE, and grade 5= death. Only those hematology and coagulation parameters in which at least 1 participant in any of the reporting arm had any shift from grade \\<=2 at baseline to grade \\>=3 post-baseline are reported in this outcome measure.","reportingStatus":"NOT_POSTED","timeFrame":"Through end of the study","title":"Cohort 3: Number of Participants With Shift From Grade <=2 at Baseline to Grade >=3 Post-Baseline in Hematology and Coagulation Parameters","type":"SECONDARY"}