{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"2.83","value":"-1.00"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"2"},{"groupId":"OG001","value":"0"}],"units":"Participants"}],"description":"Vaginal pH was used as an objective physiologic marker to determine the improvement in vaginal atrophy. pH is a measure of acidity and alkalinity and can range from 0 to 14, with 7 being neutral. Lower pH scores are acidic and higher pH scores are basic or alkaline. A normal healthy vaginal pH is 4.5. As the vaginal epithelium becomes thinner and more atrophic, the mucosa has less glycogen content and less lactobacilli to convert the glycogen into lactic acid, which results in an increase in the vaginal pH.","dispersionType":"Standard Deviation","groups":[{"description":"Subjects randomized to the Intrarosa® arm will use 6.5 mg daily for 12 weeks (±1 week).","id":"OG000","title":"Intrarosa & Standard of Care Aromatase Inhibitor"},{"description":"Subjects randomized to the Replens™ arm will use a vaginal applicator two times per week for 12 weeks (±1 week).","id":"OG001","title":"Replens & Standard of Care Aromatase Inhibitor"}],"paramType":"MEAN","populationDescription":"Out of 8 participants assigned to a treatment arm, only 2 had vaginal pH measured at both the baseline and 12-week visits.","reportingStatus":"POSTED","timeFrame":"12 weeks (±1 week)","title":"Difference in Vaginal pH From Baseline to Week 12","type":"SECONDARY","unitOfMeasure":"Units on a scale"}