{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"1.20","upperLimit":"1.72","value":"1.46"},{"groupId":"OG001","lowerLimit":"1.12","upperLimit":"1.68","value":"1.40"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"141"},{"groupId":"OG001","value":"134"}],"units":"Participants"}],"description":"measured by M. D. Anderson Symptom Inventory Blood and Marrow Transplantaion (MDASI-BMT). The symptoms rated are feeling physically sick, weak, diarrhea, mouth sores, and bleeding. All symptoms are rated with reference to \"the last 24 hours\" on 0-10 numeric scales from \"not present\" to \"as bad as you can imagine.\" MDASIBMT Total Symptom Severity score will serve as the symptom burden primary endpoint. The MDASI assesses the severity of symptoms at their worst in the last 24 hours on a 0-10 numerical scale with 0 being \"not present\" and 10 being \"as bad as you can imagine. Total symptom severity was calculated by averaging all 18 items in the scale","dispersionType":"95% Confidence Interval","groups":[{"description":"Acupuncture will start on Day 0 and continue once daily to Day 15, as long as the patient is inpatient or comes to the clinic for post-transplantation follow-up. to prevent severe pain. If acupuncture does not prevent severe pain, the participant will receive opioid medication as backup pain relief.\n\nAcupuncture: Acupuncture treatments will be scheduled to cover the period of high symptom burden. Acupuncture will start on Day 0 and continue once daily to Day 15, as long as the patient is inpatient or comes to the clinic for post-transplantation follow-up. Electrical stimulation (e-acupuncture) may be applied to the ST36 and SP6 points when appropriate as per standard acupuncture practice.\n\nopioid: All study patients will receive the usual HSCT care and pain management regimens (usually opioids) as per standard practice at the study institution.\n\nAssessments: Participants will be asked to complete patient reported outcomes assessments online using REDCap or, If they prefer, via pencil and paper or over the phone. Assessments at baseline (within 4 weeks before HiChemo) and on or about days 7, 15, 30, and 90 after the first dose of HiChemo.","id":"OG000","title":"Acupuncture Plus Usual Care"},{"description":"Will receive only the usual pain management approach, which includes opioid medication when needed for severe pain, according to the routine guidelines for their care.\n\nopioid: All study patients will receive the usual HSCT care and pain management regimens (usually opioids) as per standard practice at the study institution.\n\nAssessments: Participants will be asked to complete patient reported outcomes assessments online using REDCap or, If they prefer, via pencil and paper or over the phone. Assessments at baseline (within 4 weeks before HiChemo) and on or about days 7, 15, 30, and 90 after the first dose of HiChemo.","id":"OG001","title":"Usual Care"}],"paramType":"MEAN","reportingStatus":"POSTED","timeFrame":"At Day 90","title":"Symptom Burden","type":"PRIMARY","unitOfMeasure":"MDASIBMT Total Symptom Severity score"}