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insufficiency"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"0"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"0"},{"groupId":"OG004","value":"0"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"1"},{"groupId":"OG008","value":"0"},{"groupId":"OG009","value":"0"},{"groupId":"OG010","value":"0"},{"groupId":"OG011","value":"0"},{"groupId":"OG012","value":"0"},{"groupId":"OG013","value":"0"},{"groupId":"OG014","value":"0"},{"groupId":"OG015","value":"0"}]}],"title":"Grade 3 Blood bilirubin 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injury"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"0"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"0"},{"groupId":"OG004","value":"0"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"0"},{"groupId":"OG009","value":"0"},{"groupId":"OG010","value":"0"},{"groupId":"OG011","value":"0"},{"groupId":"OG012","value":"0"},{"groupId":"OG013","value":"0"},{"groupId":"OG014","value":"0"},{"groupId":"OG015","value":"0"}]}],"title":"Grade 3 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Adverse events were assessed by the Common Terminology Criteria for Adverse Events (CTCAE v5.0). A non-serious adverse event is any untoward medical occurrence. A serious adverse event is an adverse event or suspected adverse reaction that results in death, a life-threatening adverse drug experience, hospitalization, disruption of the ability to conduct normal life functions, congenital anomaly/birth defect or important medical events that jeopardize the patient or subject and may require medical or surgical intervention to prevent one of the previous outcomes mentioned. Grade 1 is mild. Grade 2 is moderate. Grade 3 is severe. Grade 4 is life-threatening. Grade 5 is death related to adverse event.","groups":[{"description":"Arm 1, Cohort 1, Dose Level -1: Serious AE's","id":"OG000","title":"Arm 1, Cohort 1, Dose Level -1, Dose Escalation Lenalidomide - Serious AE's"},{"description":"Arm 1, Cohort 1, Dose Level -1: Non-Serious AE's","id":"OG001","title":"Arm 1, Cohort 1, Dose Level -1, Dose Escalation Lenalidomide - Non-Serious AE's"},{"description":"Arm 1, Cohort 1, Dose Level 1: Serious AE's","id":"OG002","title":"Arm 1, Cohort 1, Dose Level 1, Dose Expansion Lenalidomide - Serious AE's"},{"description":"Arm 1, Cohort 1, Dose Level 1: Non-Serious AE's","id":"OG003","title":"Arm 1, Cohort 1, Dose Level 1, Dose Expansion Lenalidomide - Non-Serious AE's"},{"description":"Arm 1, Cohort 1, Dose Level 2: Serious AE's","id":"OG004","title":"Arm 1, Cohort 1, Dose Level 2, Dose Escalation Lenalidomide - Serious AE's"},{"description":"Arm 1, Cohort 1, Dose Level 2: Non-Serious AE's","id":"OG005","title":"Arm 1, Cohort 1, Dose Level 2, Dose Escalation Lenalidomide - Non-Serious AE's"},{"description":"Arm 1, Cohort 1, Dose Level 3: Serious AE's","id":"OG006","title":"Arm 1, Cohort 1, Dose Level 3 Dose Escalation - Serious AE's"},{"description":"Arm 1, Cohort 1, Dose Level 3: Non-Serious AE's","id":"OG007","title":"Arm 1, Cohort 1, Dose Level 3 Dose Escalation - Non-Serious AE's"},{"description":"Arm 1, Cohort 1, Dose Level 4: Serious AE's","id":"OG008","title":"Arm 1, Cohort 1, Dose Level 4, Dose Escalation Lenalidomide - Serious AE's"},{"description":"Arm 1, Cohort 1, Dose Level 4: Non-Serious AE's","id":"OG009","title":"Arm 1, Cohort 1, Dose Level 4, Dose Escalation Lenalidomide - Non-Serious AE's"},{"description":"Arm 2, Cohort 2, Dose Level 2: Serious AE's","id":"OG010","title":"Arm 2, Cohort 2, Dose Level 2, Dose Expansion Lenalidomide - Serious AE's"},{"description":"Arm 2, Cohort 2, Dose Level 2: Non-Serious AE's","id":"OG011","title":"Arm 2, Cohort 2, Dose Level 2, Dose Expansion Lenalidomide - Non-Serious AE's"},{"description":"Arm 2, Cohort 2, Dose Level 4: Serious AE's","id":"OG012","title":"Arm 2, Cohort 2, Dose Level 4, Dose Expansion Lenalidomide - Serious AE's"},{"description":"Arm 2, Cohort 2, Dose Level 4: Non-Serious AE's","id":"OG013","title":"Arm 2, Cohort 2, Dose Level 4, Dose Expansion Lenalidomide - Non-Serious AE's"},{"description":"Arm 3, Cohort 2, Dose Level 4: Serious AE's","id":"OG014","title":"Arm 3, Cohort 2, Dose Level 4, Dose Expansion Lenalidomide - Serious AE's"},{"description":"Arm 3, Cohort 2, Dose Level 4: Non-Serious AE's","id":"OG015","title":"Arm 3, Cohort 2, Dose Level 4, Dose Expansion Lenalidomide - Non-Serious AE's"}],"paramType":"NUMBER","reportingStatus":"POSTED","timeFrame":"6 cycles (each cycle is 28 days)","title":"Rate and Severity of Serious and/or Non-serious Adverse Events (AE's) by Grade and Type of Toxicity","type":"PRIMARY","unitOfMeasure":"adverse events"}