{"analyses":[{"ciLowerLimit":"-0.42","ciNumSides":"TWO_SIDED","ciPctValue":"95","ciUpperLimit":"0.08","dispersionType":"STANDARD_ERROR_OF_MEAN","dispersionValue":"0.128","groupDescription":"Day 4","groupIds":["OG000","OG001"],"nonInferiorityType":"SUPERIORITY","pValue":"0.191","paramType":"LS Mean Difference (Final Values)","paramValue":"-0.17","statisticalMethod":"Mixed Models Analysis"},{"ciLowerLimit":"-0.49","ciNumSides":"TWO_SIDED","ciPctValue":"95","ciUpperLimit":"0.14","dispersionType":"STANDARD_ERROR_OF_MEAN","dispersionValue":"0.161","groupDescription":"Day 7","groupIds":["OG000","OG001"],"nonInferiorityType":"SUPERIORITY","pValue":"0.278","paramType":"LS Mean Difference (Final Values)","paramValue":"-0.17","statisticalMethod":"Mixed Models Analysis"},{"ciLowerLimit":"-0.49","ciNumSides":"TWO_SIDED","ciPctValue":"95","ciUpperLimit":"0.24","dispersionType":"STANDARD_ERROR_OF_MEAN","dispersionValue":"0.187","groupDescription":"Day 10","groupIds":["OG000","OG001"],"nonInferiorityType":"SUPERIORITY","pValue":"0.496","paramType":"LS Mean Difference (Final Values)","paramValue":"-0.13","statisticalMethod":"Mixed Models Analysis"},{"ciLowerLimit":"-0.70","ciNumSides":"TWO_SIDED","ciPctValue":"95","ciUpperLimit":"0.19","dispersionType":"STANDARD_ERROR_OF_MEAN","dispersionValue":"0.226","groupDescription":"Day 14","groupIds":["OG000","OG001"],"nonInferiorityType":"SUPERIORITY","pValue":"0.263","paramType":"LS Mean Difference (Final Values)","paramValue":"-0.25","statisticalMethod":"Mixed Models Analysis"}],"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.127","value":"-0.59"},{"groupId":"OG001","spread":"0.125","value":"-0.76"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"636"},{"groupId":"OG001","value":"647"}],"units":"Participants"}],"title":"Day 4"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.145","value":"-0.86"},{"groupId":"OG001","spread":"0.143","value":"-1.04"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"488"},{"groupId":"OG001","value":"485"}],"units":"Participants"}],"title":"Day 7"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.160","value":"-1.33"},{"groupId":"OG001","spread":"0.158","value":"-1.45"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"388"},{"groupId":"OG001","value":"399"}],"units":"Participants"}],"title":"Day 10"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.183","value":"-1.41"},{"groupId":"OG001","spread":"0.182","value":"-1.66"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"300"},{"groupId":"OG001","value":"299"}],"units":"Participants"}],"title":"Day 14"}],"denoms":[{"counts":[{"groupId":"OG000","value":"636"},{"groupId":"OG001","value":"647"}],"units":"Participants"}],"description":"The NEWS score is used to detect and report changes in illness severity in participants with acute illness to identify participants at risk for poor outcomes. The score is based on six physiological parameters (Respiration rate; oxygen saturation; temperature; systolic blood pressure; heart (pulse) rate, and level of consciousness). A score is assigned to each parameter, and the sum of the score represents the participant's risk of poor outcomes with a minimum score of 0 representing the better outcome, a score of 7 or greater reflects high clinical risk for worsening and maximum score of 19 representing the worse outcome.","dispersionType":"Standard Error","groups":[{"description":"Placebo administered orally QD with standard of care.","id":"OG000","title":"Placebo + SOC"},{"description":"4 mg baricitinib administered orally QD with standard of care.","id":"OG001","title":"Baricitinib + SOC"}],"paramType":"LEAST_SQUARES_MEAN","populationDescription":"All participants randomly assigned to study intervention with baseline and 1 postbaseline observation.","reportingStatus":"POSTED","timeFrame":"Baseline, Day 4; Baseline, Day 7; Baseline, Day 10; Baseline, Day 14","title":"Mean Change From Baseline on the National Early Warning Score (NEWS)","type":"SECONDARY","unitOfMeasure":"score on a scale"}