{"denoms":[{"counts":[{"groupId":"BG000","value":"22"},{"groupId":"BG001","value":"20"},{"groupId":"BG002","value":"20"},{"groupId":"BG003","value":"62"}],"units":"Participants"}],"groups":[{"description":"22 cases of malignant ovarian germ cell tumors ; include Dysgerminoma , yolk sac tumor and immature teratomas will be treated by anti P16 antibody .\n\np16INK4a Recombinant Rabbit Monoclonal Antibody (RM267): Treatment of slides that cut from paraffin embedded blocks related to groups by immunohistochemical method by p16INK4a Recombinant Rabbit Monoclonal Antibody (RM267).","id":"BG000","title":"Malignant Ovarian Germ Cell Tumors ( MOGCTs)."},{"description":"20 cases of mature teratomas will be treated by anti P16 antibody .","id":"BG001","title":"Mature Cystic Teratomas."},{"description":"20cases of normally apparent ovaries will be treated by anti P16 antibody .","id":"BG002","title":"Normally Apparent Ovaries."},{"description":"Total of all reporting groups","id":"BG003","title":"Total"}],"measures":[{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","lowerLimit":"12","upperLimit":"23","value":"16.5"},{"groupId":"BG001","lowerLimit":"14","upperLimit":"50","value":"31.5"},{"groupId":"BG002","lowerLimit":"42","upperLimit":"64","value":"50"},{"groupId":"BG003","lowerLimit":"12","upperLimit":"64","value":"30"}]}]}],"dispersionType":"FULL_RANGE","paramType":"MEDIAN","title":"Age, Continuous","unitOfMeasure":"years"},{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","value":"22"},{"groupId":"BG001","value":"20"},{"groupId":"BG002","value":"20"},{"groupId":"BG003","value":"62"}],"title":"Female"},{"measurements":[{"groupId":"BG000","value":"0"},{"groupId":"BG001","value":"0"},{"groupId":"BG002","value":"0"},{"groupId":"BG003","value":"0"}],"title":"Male"}]}],"paramType":"COUNT_OF_PARTICIPANTS","title":"Sex: Female, Male","unitOfMeasure":"Participants"},{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","value":"0"},{"groupId":"BG001","value":"0"},{"groupId":"BG002","value":"0"},{"groupId":"BG003","value":"0"}],"title":"Hispanic or Latino"},{"measurements":[{"groupId":"BG000","value":"22"},{"groupId":"BG001","value":"20"},{"groupId":"BG002","value":"20"},{"groupId":"BG003","value":"62"}],"title":"Not Hispanic or Latino"},{"measurements":[{"groupId":"BG000","value":"0"},{"groupId":"BG001","value":"0"},{"groupId":"BG002","value":"0"},{"groupId":"BG003","value":"0"}],"title":"Unknown or Not Reported"}]}],"paramType":"COUNT_OF_PARTICIPANTS","title":"Ethnicity (NIH/OMB)","unitOfMeasure":"Participants"},{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","value":"22"},{"groupId":"BG001","value":"20"},{"groupId":"BG002","value":"20"},{"groupId":"BG003","value":"62"}]}],"title":"Egypt"}],"paramType":"NUMBER","title":"Region of Enrollment","unitOfMeasure":"participants"},{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","lowerLimit":"0","upperLimit":"8","value":"7"},{"groupId":"BG001","lowerLimit":"0","upperLimit":"6","value":"4"},{"groupId":"BG002","lowerLimit":"0","upperLimit":"4","value":"0"},{"groupId":"BG003","lowerLimit":"0","upperLimit":"8","value":"6"}]}]}],"description":"Percentage of positive cells and the location of positive signals (nuclear or cytoplasmic) visually estimated for of lesions.\n\nGerman Semi-quantitative scoring system is used to evaluate P16 expression. A score according to the intensity of staining (no staining = 0, weak = 1, moderate = 2, strong= 3) And the extent of stained cells (0% = 0, 1-10% = 1, 11-50% =2, 51-80% = 3, 81-100% = 4).\n\nThe final score will be determined by multiplying the intensity scores with the extent of positivity scores of stained cells, with the minimum score of 0 and a maximum score of 12.","dispersionType":"FULL_RANGE","paramType":"MEDIAN","title":"P16 cytoplasmic expression","unitOfMeasure":"units on a scale"},{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","lowerLimit":"0","upperLimit":"8","value":"6"},{"groupId":"BG001","lowerLimit":"0","upperLimit":"5","value":"4"},{"groupId":"BG002","lowerLimit":"0","upperLimit":"3","value":"0"},{"groupId":"BG003","lowerLimit":"0","upperLimit":"8","value":"4"}]}]}],"description":"Percentage of positive cells and the location of positive signals (nuclear or cytoplasmic) visually estimated for of lesions.\n\nGerman Semi-quantitative scoring system is used to evaluate P16 expression. A score according to the intensity of staining (no staining = 0, weak = 1, moderate = 2, strong= 3) And the extent of stained cells (0% = 0, 1-10% = 1, 11-50% =2, 51-80% = 3, 81-100% = 4).\n\nThe final score will be determined by multiplying the intensity scores with the extent of positivity scores of stained cells, with the minimum score of 0 and a maximum score of 12.","dispersionType":"FULL_RANGE","paramType":"MEDIAN","title":"P16 nuclear expression","unitOfMeasure":"units on a scale"}]}