{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"104","value":"566"},{"groupId":"OG001","spread":"60","value":"728"},{"groupId":"OG002","spread":"77","value":"728"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"3"},{"groupId":"OG001","value":"8"},{"groupId":"OG002","value":"14"}],"units":"Participants"}],"title":"Cycle 1, Day 1"},{"categories":[{"measurements":[{"comment":"Geometric Mean and Geometric Coefficient of Variation couldn't be calculated as there were only two participants. Individual values reported: 994.32 ng\\*h/mL and 2247.03 ng\\*h/mL.","groupId":"OG000","spread":"NA","value":"NA"},{"groupId":"OG001","spread":"27","value":"600"},{"groupId":"OG002","spread":"57","value":"1060"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"2"},{"groupId":"OG001","value":"5"},{"groupId":"OG002","value":"10"}],"units":"Participants"}],"title":"Cycle 2, Day 1"}],"denoms":[{"counts":[{"groupId":"OG000","value":"3"},{"groupId":"OG001","value":"8"},{"groupId":"OG002","value":"14"}],"units":"Participants"}],"description":"PK: AUC0-tlast was reported.","dispersionType":"Geometric Coefficient of Variation","groups":[{"description":"All part B participants who received 70 mg/m² abemaciclib were included under this arm.","id":"OG000","title":"Part B: 70 mg/m² Abemaciclib"},{"description":"All part B participants who received 90 mg/m² abemaciclib were included under this arm.","id":"OG001","title":"Part B: 90 mg/m² Abemaciclib"},{"description":"All part B participants who received 115 mg/m² abemaciclib were included under this arm.","id":"OG002","title":"Part B: 115 mg/m² Abemaciclib"}],"paramType":"GEOMETRIC_MEAN","populationDescription":"All participants in Part B who received at least one dose of abemaciclib and had evaluable PK data. Per planned analysis, PK analysis was performed as per the dose of study drug received.","reportingStatus":"POSTED","timeFrame":"Pre-dose, 1, 2.5, 4, and 6 hours post Day 1 dose of Cycle 1 and Cycle 2 (21 Day Cycle)","title":"PK: AUC0-tlast of Abemaciclib in Part B","type":"PRIMARY","unitOfMeasure":"ng*h/mL"}