{"description":"Safety analysis set included all enrolled participants who received at least 1 dose of ibrutinib. As ibrutinib and rituximab were administered as a combination treatment, adverse events analyses was not performed per the study intervention and thus combined data are presented.","eventGroups":[{"deathsNumAffected":0,"deathsNumAtRisk":16,"description":"Treatment naive or relapsed/refractory Waldenstrom's Macroglobulinemia (WM) Japanese participants received ibrutinib 420 milligrams (mg) (3\\*140 mg capsules) orally, once daily, from Day 1 of Week 1 until disease progression or unacceptable toxicity along with rituximab 375 milligrams per square meter (mg/m\\^2) intravenously (IV) weekly for 4 consecutive weeks (Day 1 of Weeks 1 to 4), followed by a second course of once-weekly rituximab for 4 consecutive weeks (from Week 17 to 20) after a 12-week interval.","id":"EG000","otherNumAffected":16,"otherNumAtRisk":16,"seriousNumAffected":4,"seriousNumAtRisk":16,"title":"Ibrutinib + Rituximab"}],"frequencyThreshold":"5","otherEvents":[{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","organSystem":"Blood and lymphatic system disorders","sourceVocabulary":"MedDRA Version 24.0","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":16}],"term":"Anaemia"},{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","organSystem":"Blood and lymphatic system disorders","sourceVocabulary":"MedDRA Version 24.0","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":16}],"term":"Iron Deficiency Anaemia"},{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","organSystem":"Blood and lymphatic system disorders","sourceVocabulary":"MedDRA Version 24.0","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":16}],"term":"Neutropenia"},{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","organSystem":"Blood and lymphatic system disorders","sourceVocabulary":"MedDRA Version 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infestations","sourceVocabulary":"MedDRA Version 24.0","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":16}],"term":"Acute Sinusitis"},{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","organSystem":"Infections and infestations","sourceVocabulary":"MedDRA Version 24.0","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":16}],"term":"Cellulitis"},{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","organSystem":"Infections and infestations","sourceVocabulary":"MedDRA Version 24.0","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":16}],"term":"Cystitis"},{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","organSystem":"Infections and infestations","sourceVocabulary":"MedDRA Version 24.0","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":16}],"term":"Fungal Skin Infection"},{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","organSystem":"Infections and infestations","sourceVocabulary":"MedDRA Version 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Infection"},{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","organSystem":"Infections and infestations","sourceVocabulary":"MedDRA Version 24.0","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":16}],"term":"Urethritis"},{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","organSystem":"Infections and infestations","sourceVocabulary":"MedDRA Version 24.0","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":16}],"term":"Urinary Tract Infection"},{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","organSystem":"Infections and infestations","sourceVocabulary":"MedDRA Version 24.0","stats":[{"groupId":"EG000","numAffected":2,"numAtRisk":16}],"term":"Viral Infection"},{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","organSystem":"Injury, poisoning and procedural complications","sourceVocabulary":"MedDRA Version 24.0","stats":[{"groupId":"EG000","numAffected":3,"numAtRisk":16}],"term":"Contusion"},{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","organSystem":"Injury, poisoning and procedural 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