{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"0","upperLimit":"2","value":"0"}]}],"title":"DIGEST grade for Chemo-IO alone treatment group: Baseline"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"0","upperLimit":"1","value":"1"}]}],"title":"DIGEST grade for Chemo-IO alone treatment group: 6M Post"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"0","upperLimit":"1","value":"0"}]}],"title":"DIGEST grade for Chemo-IO alone treatment group: Long Term FU"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"0","upperLimit":"2","value":"1"}]}],"title":"DIGEST grade for RT/Surgery treatment group: Baseline"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"0","upperLimit":"3","value":"2"}]}],"title":"DIGEST grade for RT/Surgery treatment group: 6M Post"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"0","upperLimit":"3","value":"1"}]}],"title":"DIGEST grade for RT/Surgery treatment group: Long Term FU"}],"denoms":[{"counts":[{"groupId":"OG000","value":"23"}],"units":"Participants"}],"description":"To determine swallow function using Dynamic Imaging Grade of Swallowing Toxicity (DIGEST). DIGEST is a validated psychometric tool used during modified barium swallow studies (MBSSs) to grade swallowing safety, efficiency, and overall pharyngeal swallow function. Scores ranging from 0 to 4, where 0 indicates no impairment, 1=mild, 2=moderate, 3=severe, 4=life threatening. The DIGEST grade was collected at three time points: baseline, 6 months post-treatment and long-term follow-up. One subject without any DIGEST data was excluded from analysis. A linear mixed-effects model was used to evaluate the effects of treatment group (chemo-IO alone vs. radiation/surgery) and time on DIGEST grade across three time points.","dispersionType":"Full Range","groups":[{"description":"cis 75 mg/m2 (SOC), doce 74 mg/m2 (SOC), pembro 200mg (Exp), Q3W IV","id":"OG000","title":"Experimental (Cis/Doce/Pembro)"}],"paramType":"MEDIAN","reportingStatus":"POSTED","timeFrame":"baseline, 6 months post treatment, long-term follow up (up to two years)","title":"DIGEST","type":"SECONDARY","unitOfMeasure":"score on a scale"}