{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"9.93","value":"60.80"},{"groupId":"OG001","spread":"10.06","value":"60.52"},{"groupId":"OG002","spread":"9.35","value":"59.78"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"115"},{"groupId":"OG001","value":"104"},{"groupId":"OG002","value":"208"}],"units":"Participants"}],"title":"Pre-intervention (Baseline)"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"11.56","value":"62.88"},{"groupId":"OG001","spread":"9.08","value":"61.50"},{"groupId":"OG002","spread":"10.27","value":"61.42"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"75"},{"groupId":"OG001","value":"62"},{"groupId":"OG002","value":"142"}],"units":"Participants"}],"title":"12-month post-intervention"}],"denoms":[{"counts":[{"groupId":"OG000","value":"115"},{"groupId":"OG001","value":"104"},{"groupId":"OG002","value":"208"}],"units":"Participants"}],"description":"High-density lipoprotein (HDL) cholesterol will be assessed using dried blood spot (DBS) samples collected via fingerstick following a 12-hour fast. Blood spots will be dried and stored according to standard protocols, and DBS eluents will be batch-tested against known standards to determine HDL cholesterol.\n\nOutcome measure is mg/dL of HDL Range (adults): typically, 20 to 100 mg/dL Higher HDL cholesterol indicates a better (protective) cardiovascular outcome.","dispersionType":"Standard Deviation","groups":[{"description":"Participants will receive and participate in web-based sessions that focus on diet for 6 months, followed by exercise for another 6 months. Participants will be encouraged to track their diet and weight for the first 6 months and to log their data in the intervention website, during the second 6 months they will be asked to log their physical activity data (minutes and step counts). Tailored feedback and goal recommendations will be provided through the website. Participants will also receive access to resources for relevant behavioral topics. All participants will be invited to participate in the secret Facebook group for the project (though participation is optional).","id":"OG000","title":"Project 1: Diet-Exercise"},{"description":"Participants will receive and participate in web-based sessions that focus on diet for 6 months, followed by exercise for another 6 months. Participants will be encouraged to track their diet and weight for the first 6 months and to log their data in the intervention website, during the second 6 months they will be asked to log their physical activity data (minutes and step counts). Tailored feedback and goal recommendations will be provided through the website. Participants will also receive access to resources for relevant behavioral topics. All participants will be invited to participate in the secret Facebook group for the project (though participation is optional).","id":"OG001","title":"Project 2: Exercise-Diet"},{"description":"Participants will receive the diet and exercise content simultaneously in combined web-based sessions. Participants will receive and participate in web-based sessions that focus on diet and exercise for 12 months. Participants will be encouraged to track their diet, weight and physical activity data (minutes and step counts). Tailored feedback and goal recommendations will be provided through the website. Participants will also receive access to resources for relevant behavioral topics. All participants will be invited to participate in the secret Facebook group for the project (though participation is optional).","id":"OG002","title":"Project 3: Combined Diet and Exercise"}],"paramType":"MEAN","populationDescription":"The number of participants analyzed differ between baseline and 12 months due to withdrawal by participant or loss to follow up.","reportingStatus":"POSTED","timeFrame":"Pre-intervention (Baseline), 12-month post-intervention","title":"Circulating Biomarkers \"HDL\"","type":"OTHER_PRE_SPECIFIED","unitOfMeasure":"MG/DL"}