{"description":"Serious and non-serious AEs were analyzed on safety population which included all participants who received at least 1 dose of study treatment; and all-cause mortality was analyzed on IIT set which included all participants who were randomized in the study.","eventGroups":[{"deathsNumAffected":12,"deathsNumAtRisk":44,"description":"Participants received carfilzomib 20 milligram per meter square (mg/m\\^2) intravenously (IV) on Cycle 1 Day 1 and then 70 mg/m\\^2 on Cycle 1 Days 8 and 15, and thereafter on Days 1, 8, 15 from Cycle 2 onwards. Participants received dexamethasone 20 milligrams (mg) on Cycle 1 Days 1 and 2, and 40 mg IV or orally on Days 8, 15, 22 of Cycle 1. Participants then received dexamethasone 40 mg IV or orally on Days 1, 8, 15 and 22 of Cycles 2-9, then on Days 1, 8, 15 from Cycle 10 onwards, until confirmed progressive disease (PD), death, intolerable toxicity, start of a new treatment for multiple myeloma, withdrawal of consent, or end of the study, whichever occurs first. Each cycle of 28 days.","id":"EG000","otherNumAffected":39,"otherNumAtRisk":43,"seriousNumAffected":20,"seriousNumAtRisk":43,"title":"Arm A: Carfilzomib+Dexamethasone (Kd)"},{"deathsNumAffected":8,"deathsNumAtRisk":44,"description":"Participants received daratumumab 1800 mg by SC injection (Dara-SC) on Days 1, 8, 15, 22 of Cycle 1 and 2, Days 1 and 15 of Cycle 3-6, and on Day 1 from Cycle 7 onwards. Participants received carfilzomib 20 mg/m\\^2 IV on Cycle 1 Day 1 and then 70 mg/m\\^2 on Cycle 1 Days 8 and 15, and Days 1, 8 and 15 from Cycle 2 onwards. Participants received dexamethasone 20 mg on Cycle 1 Days 1 and 2 and 40 mg IV or orally on Days 8, 15, 22 of Cycle 1. Participants then received dexamethasone 40 mg IV or orally on Days 1, 8, 15 and 22 of Cycles 2-9, then on Days 1, 8, 15 from Cycle 10 onwards, until confirmed PD, death, intolerable toxicity, start of a new treatment for multiple myeloma, withdrawal of consent, or end of the study, whichever occurs first. Each cycle of 28 days.","id":"EG001","otherNumAffected":37,"otherNumAtRisk":43,"seriousNumAffected":12,"seriousNumAtRisk":43,"title":"Arm B: Dara-SC in Combination With Kd (DKd)"}],"frequencyThreshold":"5","otherEvents":[{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","organSystem":"Blood and lymphatic system disorders","sourceVocabulary":"MedDRA 24.0","stats":[{"groupId":"EG000","numAffected":14,"numAtRisk":43,"numEvents":37},{"groupId":"EG001","numAffected":11,"numAtRisk":43,"numEvents":20}],"term":"Anaemia"},{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","organSystem":"Blood and lymphatic system disorders","sourceVocabulary":"MedDRA 24.0","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":43,"numEvents":2},{"groupId":"EG001","numAffected":4,"numAtRisk":43,"numEvents":5}],"term":"Leukopenia"},{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","organSystem":"Blood and lymphatic system disorders","sourceVocabulary":"MedDRA 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