{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","value":"20"}]}],"title":"DBP, Any Grade Increase"},{"categories":[{"measurements":[{"groupId":"OG000","value":"12"}]}],"title":"DBP, Increase to Grade 2"},{"categories":[{"measurements":[{"groupId":"OG000","value":"2"}]}],"title":"DBP, Increase to Grade 3"},{"categories":[{"measurements":[{"groupId":"OG000","value":"24"}]}],"title":"SBP, Any Grade Increase"},{"categories":[{"measurements":[{"groupId":"OG000","value":"16"}]}],"title":"SBP, Increase to Grade 2"},{"categories":[{"measurements":[{"groupId":"OG000","value":"6"}]}],"title":"SBP, Increase to Grade 3"}],"denoms":[{"counts":[{"groupId":"OG000","value":"28"}],"units":"Participants"}],"description":"DBP and SBP were measured after resting for at least 5 minutes in a supine or semi-recumbent position. They were graded according to NCI-CTCAE version 4.0. For SBP: Grade 0 (\\<=120 millimeter of mercury \\[mmHg\\]), Grade 1 (121-139 mmHg), Grade 2 (140-159 mmHg), Grade 3 (\\>=160 mmHg). For DBP: Grade 0 (\\<=80 mmHg), Grade 1 (81-89 mmHg), Grade 2 (90-99 mmHg), Grade 3 (\\>=100 mmHg). Higher grade indicates greater severity. Baseline was defined as the most recent, non-missing value prior to or on the first study treatment dose date. An increase is defined as an increase in grade relative to Baseline grade. Data for worst-case post Baseline with any grade increase and a maximum post-baseline grade increase to Grade 3 from their baseline grade are presented.","groups":[{"description":"Participants were administered belantamab mafodotin with recommended phase 2 dose (RP2D) of 2.5 mg/kg in combination with 200 mg of pembrolizumab via IV infusion on Day 1 of each 21-day Cycle up to until disease progression, intolerable toxicity, informed consent withdrawal, or for a maximum of 35 cycles.","id":"OG000","title":"Main Study Phase- Part 2: Belantamab Mafodotin 2.5 mg/kg + Pembrolizumab 200 mg Expansion"}],"paramType":"COUNT_OF_PARTICIPANTS","populationDescription":"All Treated Population","reportingStatus":"POSTED","timeFrame":"Baseline (Day 1) and up to approximately 178 weeks","title":"Part 2 - Number of Participants With Worst-case Grade Change From Baseline in Vital Signs: DBP and SBP","type":"SECONDARY","unitOfMeasure":"Participants"}