{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"127","value":"433"},{"groupId":"OG001","spread":"80.1","value":"1509"},{"groupId":"OG002","spread":"38.4","value":"2067"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"9"},{"groupId":"OG001","value":"3"},{"groupId":"OG002","value":"6"}],"units":"Participants"}],"description":"Evaluate the Area under the time-concentration curve \\[AUC\\] of ONM-100 at 1 mg/kg, 2 mg/kg, and 3 mg/kg doses.","dispersionType":"Geometric Coefficient of Variation","groups":[{"description":"Patients receiving a single IV administration of ONM-100 at 1 mg/kg.","id":"OG000","title":"ONM-100 at a Dose of 1 mg/kg"},{"description":"Patients received a single IV administration of ONM-100 at 2 mg/kg.","id":"OG001","title":"ONM-100 at a Dose of 2 mg/kg"},{"description":"Patients receiving a single IV administration of ONM-100 at 3 mg/kg.","id":"OG002","title":"ONM-100 at a Dose of 3 mg/kg"}],"paramType":"GEOMETRIC_MEAN","populationDescription":"The PK analysis population comprised 19 patients for whom concentration data were available. Due to sparse plasma concentrations for the majority of patients, with the exception of Cmax and Tmax, it was not possible to estimate all parameters for all patients.","reportingStatus":"POSTED","timeFrame":"6 days","title":"Evaluate Pharmacokinetic Parameters: AUC","type":"SECONDARY","unitOfMeasure":"hr x μg/mL"}