{"denomUnitsSelected":"Participants","description":"The Global Clinical Response assessment measures the patient's signs and symptoms of endogenous hypercortisolism in 7 clinical categories: 1) glucose parameters, 2) blood pressure parameters, 3) body composition parameters, 4) clinical appearance, 5) strength parameters, 6) psychiatric health/cognitive function parameters, and 7) quality of life using the Cushing QoL score. The overall response based on the totality of signs and symptoms is rated as +1 for improved, 0 for unchanged, and -1 for worsened. Each patient's final score is the median of ratings given by 3 members of the Data Review Board.","reportingStatus":"NOT_POSTED","timeFrame":"Week 22 (end of OL Phase) and up to Week 36 (Week 12 of RW Phase)","title":"Number of Patients Who Worsened, as Assessed by the Global Clinical Response, During the RW Phase","type":"OTHER_PRE_SPECIFIED"}