{"anticipatedPostingDate":"2028-07","denomUnitsSelected":"Participants","description":"Duration of MRD-negative CR is defined as interval between the first assessment at which the criteria for MRD-negative CR are met until the earliest date at which loss of MRD negativity or relapse from CR occurs. MRD negativity (MR4): \\<=0.01% BCR-ABL1/ABL1, or undetectable BCR-ABL1 transcripts in cDNA with \\>=10,000 ABL1 transcripts. CR is defined as meeting all the following for at least 4 weeks (that is, no recurrence): 1. No circulating blasts and \\<5% blasts in the BM. 2. Normal maturation of all cellular components in the BM. 3. No extramedullary disease (CNS involvement, lymphadenopathy, splenomegaly, skin/gum infiltration, testicular mass). 4. ANC \\>1000/mcL (or \\>1.0\\*10\\^9/L). 5. Platelets \\>100,000/mcL (or \\>100\\*10\\^9/L). Relapse from CR: Reappearance of blasts in the blood or BM (\\>=5%) or in any extramedullary site after a CR.","reportingStatus":"NOT_POSTED","timeFrame":"Up to approximately 3 to 6 years","title":"Duration of MRD-Negative CR","type":"SECONDARY"}