{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"2.836","value":"-1.12"}]}],"title":"Fatigue"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"2.099","value":"-0.80"}]}],"title":"Spots"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"2.302","value":"-0.94"}]}],"title":"Itching"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"2.351","value":"-0.78"}]}],"title":"Flushing"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"2.439","value":"-1.51"}]}],"title":"Abdominal Pain"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"1.723","value":"-0.75"}]}],"title":"Nausea"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"1.004","value":"-0.03"}]}],"title":"Vomiting"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"1.970","value":"-0.53"}]}],"title":"Diarrhea"}],"denoms":[{"counts":[{"groupId":"OG000","value":"93"}],"units":"Participants"}],"description":"The AdvSM-SAF is a 10-item questionnaire that assesses symptoms and functional domains specific to AdvSM. Individual symptom scores are generated based on average scores for each 7-day period. Eight symptoms are scored on a scale of 0 to 10 for severity. An increase in score represents a worse symptoms outcome. Participants completed the AdvSM-SAF daily using an eDiary.","dispersionType":"Standard Deviation","groups":[{"description":"Avapritinib was administered once daily as an immediate-release tablet, orally, in 28-day cycles.","id":"OG000","title":"Avapritinib"}],"paramType":"MEAN","populationDescription":"Safety Population: all participants who received ≥1 dose of avapritinib. Here, 'Number Analyzed' signifies those participants evaluable for this outcome measure at the specified timepoint.","reportingStatus":"POSTED","timeFrame":"Baseline, Month 10","title":"Mean Change From Baseline in AdvSM-SAF Individual Symptom Scores (Severity) at Month 10","type":"SECONDARY","unitOfMeasure":"Score on a Scale"}