{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"449","value":"48700"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"74"}],"units":"Participants"}],"title":"AUC 0 - 28d"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"281","value":"93700"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"66"}],"units":"Participants"}],"title":"AUC 0 - 84d"}],"denoms":[{"counts":[{"groupId":"OG000","value":"74"}],"units":"Participants"}],"description":"AUC0-28 is the area under curve (AUC) from time zero to day 28 in peripheral blood. AUC0-84d is the AUC from time zero to day 84 in peripheral blood. Actual sampling times were taken into consideration for the calculation of cellular kinetic parameters.","dispersionType":"Geometric Coefficient of Variation","groups":[{"description":"All participants who were enrolled in the study","id":"OG000","title":"CTL019"}],"paramType":"GEOMETRIC_MEAN","populationDescription":"Participants in the Cellular kinetic set (CKAS) with an available value for the outcome measure. The CKAS consisted of patients in the Efficacy analysis set who provided an evaluable cellular kinetic profile (at least 1 cellular kinetic parameter).","reportingStatus":"POSTED","timeFrame":"0 to 28 days after infusion, 0 to 84 days after infusion","title":"AUC0-28d and AUC0-84d; Cellular Kinetic Parameter of Tisagenlecleucel Transgene Levels by qPCR, Based on Clinical Response by IRC Assessment","type":"SECONDARY","unitOfMeasure":"Copies/ug*days"}