{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"25.6","upperLimit":"45.4","value":"35"},{"groupId":"OG001","lowerLimit":"28.8","upperLimit":"48.7","value":"38"},{"groupId":"OG002","lowerLimit":"38.7","upperLimit":"78.9","value":"60"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"97"},{"groupId":"OG001","value":"99"},{"groupId":"OG002","value":"25"}],"units":"Participants"}],"description":"CBR was determined by the investigator according to the 2016 IMWG response criteria. CBR was calculated as the percentage of participants with a confirmed minimal response (MR) or better (i.e., MR, PR, VGPR, CR and sCR). Confidence intervals were based on the exact method. Percentage values are rounded off.","dispersionType":"95% Confidence Interval","groups":[{"description":"Participants were administered frozen liquid (30 mg/vial solution in a single use vial) at a dose of 2.5 mg/kg GSK2857916 as IV solution once every three weeks for a maximum of up to 39 cycles (1 cycle= 21 days). Frozen liquid was diluted with 0.9 percent saline.","id":"OG000","title":"Main Study: GSK2857916 2.5 mg/kg (Frozen Liquid)"},{"description":"Participants were administered frozen liquid (30 mg/vial solution in a single use vial) at a dose of 3.4 mg/kg GSK2857916 as IV solution once every three weeks for a maximum of up to 32 cycles (1 cycle= 21 days). Frozen liquid was diluted with 0.9 percent saline.","id":"OG001","title":"Main Study: GSK2857916 3.4 mg/kg (Frozen Liquid)"},{"description":"Participants were administered lyophilized powder (100 mg/vial in a single use vial) at a dose of 3.4 mg/kg GSK2857916 given IV for a maximum of 35 cycles (1 cycle= 21 days). Lyophilized powder was reconstituted using water for injection.","id":"OG002","title":"Main Study: GSK2857916 3.4 mg/kg (Lyophilized)"}],"paramType":"NUMBER","populationDescription":"Full Analysis Population","reportingStatus":"POSTED","timeFrame":"Up to 186 weeks","title":"Clinical Benefit Rate (CBR) by Investigator Assessment (Full Analysis Population)","type":"SECONDARY","unitOfMeasure":"Percentage of Participants"}