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C14D22"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"37.09","value":"23.81"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"7"},{"groupId":"OG001","value":"0"}],"units":"Participants"}],"title":"Hair loss C15D1"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"19.25","value":"16.67"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"4"},{"groupId":"OG001","value":"0"}],"units":"Participants"}],"title":"Hair loss C15D22"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"18.26","value":"13.33"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"5"},{"groupId":"OG001","value":"0"}],"units":"Participants"}],"title":"Hair loss C16D1"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"19.25","value":"16.67"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"4"},{"groupId":"OG001","value":"0"}],"units":"Participants"}],"title":"Hair loss C16D22"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"31.91","value":"8.33"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"4"},{"groupId":"OG001","value":"0"}],"units":"Participants"}],"title":"Hair loss C17D1"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"27.22","value":"0.00"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"4"},{"groupId":"OG001","value":"0"}],"units":"Participants"}],"title":"Hair loss C17D22"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"27.22","value":"0.00"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"4"},{"groupId":"OG001","value":"0"}],"units":"Participants"}],"title":"Hair loss C18D1"},{"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"0"}],"units":"Participants"}],"title":"Hair loss C18D22"},{"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"0"}],"units":"Participants"}],"title":"Hair loss C19D1"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"31.91","value":"41.67"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"4"},{"groupId":"OG001","value":"0"}],"units":"Participants"}],"title":"Hair loss C19D22"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"45.54","value":"-11.11"},{"groupId":"OG001","spread":"22.92","value":"18.18"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"6"},{"groupId":"OG001","value":"11"}],"units":"Participants"}],"title":"Hair loss 30 day follow up"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"33.61","value":"21.43"},{"groupId":"OG001","spread":"25.32","value":"16.67"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"14"},{"groupId":"OG001","value":"14"}],"units":"Participants"}],"title":"Hair loss 90 day follow up"}],"denoms":[{"counts":[{"groupId":"OG000","value":"257"},{"groupId":"OG001","value":"257"}],"units":"Participants"}],"description":"The EORTC-QLQ-OG25 consists of a 25-item instrument that evaluates gastric and GEJ cancer-specific symptoms such as stomach discomfort, difficulties eating and swallowing and indigestion. This module consists of 6 scales: dysphagia (3 items), eating restrictions (4 items), reflux (2 items), odynophagia (2 items), pain and discomfort (2 items) and anxiety (2 items), as well as 10 single items: eating in front of others, dry mouth, trouble with taste, body image, trouble swallowing saliva, choked when swallowing, trouble with coughing, trouble talking, weight loss and hair loss. All questions have four response alternatives (1:not at all; 2:a little, 3:quite a bit, 4:very much). Questionnaire responses were transformed lineraly into scores ranging from 0 to 100 For symptom scales/items, higher scores indicate worse symptoms.","dispersionType":"Standard Deviation","groups":[{"description":"Participants received an IV infusion (as a minimum of 2-hour infusion) of zolbetuximab at a loading dose of 800 mg/m\\^2 on C1D1 followed by subsequent doses of 600 mg/m\\^2 every 3 weeks starting from C1D22 until participant meets study treatment discontinuation criteria. Participants also received up to 12 treatments of 5-fluorouracil, folinic acid and oxaliplatin (mFOLFOX6) (or components of mFOLFOX6 if some components were discontinued due to toxicity) over 4 or more cycles in which mFOLFOX6 was administered on Days 1, 15 and 29 of each cycle (5-fluorouracil administered by IV bolus 400 mg/m\\^2 over 5 to 15 minutes followed by 2400mg/m\\^2 over 46-48 hours continuous IV infusion every 2 weeks for 4 cycles. Folinic acid administered 400 mg/m\\^2 IV infusion over 2 hours; oxaliplatin administered 85 mg/m\\^2 IV infusion over 2 hours). A maximum of 12 doses of oxaliplatin was permitted. After mFOLFOX6 treatments, participants could continue to receive 5-FU and folinic acid on Days 1, 15 and 29 of each cycle at the investigator's discretion or until the participant met the study treatment discontinuation criteria. Each cycle was approximately 42 days.","id":"OG000","title":"mFOLFOX6 + Zolbetuximab"},{"description":"Participants received an IV infusion (minimum 2-hour infusion) of placebo matched to zolbetuximab on C1D1, followed by subsequent doses every 3 weeks starting from C1D22 until study treatment discontinuation criteria were met. Participants also received up to 12 treatments of mFOLFOX6 (or components if some were discontinued due to toxicity) over 4 or more cycles. mFOLFOX6 was administered on Days 1, 15, and 29 of each cycle (5-fluorouracil: 400 mg/m\\^2 IV bolus over 5-15 minutes followed by 2400mg/m\\^2 over 46-48 hours continuous IV infusion every 2 weeks for 4 cycles. Folinic acid: 400 mg/m\\^2 IV infusion over 2 hours; oxaliplatin: 85 mg/m\\^2 IV infusion over 2 hours). A maximum of 12 doses of oxaliplatin was permitted. After mFOLFOX6 treatments, participants could continue to receive 5-FU and folinic acid on Days 1, 15, and 29 of each cycle at the investigator's discretion or until study treatment discontinuation criteria were met. Each cycle was approximately 42 days.","id":"OG001","title":"mFOLFOX6+ Placebo"}],"paramType":"MEAN","populationDescription":"FAS with available data was analyzed.","reportingStatus":"POSTED","timeFrame":"Baseline, C1D22, D1 and D22 of C2 through C25, C26D1, C27D1,C28D1 30 day follow up, 90 day follow up","title":"Change From Baseline in HRQoL Measured by the QLQ-OG25 Questionnaire","type":"SECONDARY","unitOfMeasure":"unit on a scale"}