{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"1.01","upperLimit":"2.73","value":"1.87"},{"groupId":"OG001","lowerLimit":"0.83","upperLimit":"9.31","value":"5.07"},{"groupId":"OG002","lowerLimit":"3.31","upperLimit":"19.76","value":"11.54"},{"groupId":"OG003","lowerLimit":"8.95","upperLimit":"21.01","value":"14.98"},{"groupId":"OG004","lowerLimit":"0","upperLimit":"27.1","value":"13.08"},{"groupId":"OG005","lowerLimit":"0","upperLimit":"29.35","value":"29.35"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"3"},{"groupId":"OG001","value":"3"},{"groupId":"OG002","value":"3"},{"groupId":"OG003","value":"3"},{"groupId":"OG004","value":"3"},{"groupId":"OG005","value":"2"}],"units":"Participants"}],"description":"Trientine (TETA) prior to and within 24 hrs and 7 days after trientine","dispersionType":"Inter-Quartile Range","groups":[{"description":"trientine dihydrochloride: trientine dihydrochloride 300MG/CAPSUE PO daily pegylated liposomal doxorubicin: pegylated liposomal doxorubicin 40mg/m2 IV D1 carboplatin: carboplatin AUC 4 IV D1","id":"OG000","title":"Trientine With Chemotherapy Dose Level 1 (300mg)"},{"description":"trientine dihydrochloride: trientine dihydrochloride 600MG/CAPSUE PO daily pegylated liposomal doxorubicin: pegylated liposomal doxorubicin 40mg/m2 IV D1 carboplatin: carboplatin AUC 4 IV D1","id":"OG001","title":"Trientine With Chemotherapy Dose Level 2 (600mg)"},{"description":"trientine dihydrochloride: trientine dihydrochloride 900MG/CAPSUE PO daily pegylated liposomal doxorubicin: pegylated liposomal doxorubicin 40mg/m2 IV D1 carboplatin: carboplatin AUC 4 IV D1","id":"OG002","title":"Trientine With Chemotherapy Dose Level 3 (900mg)"},{"description":"trientine dihydrochloride: trientine dihydrochloride 1200MG/CAPSUE PO daily pegylated liposomal doxorubicin: pegylated liposomal doxorubicin 40mg/m2 IV D1 carboplatin: carboplatin AUC 4 IV D1","id":"OG003","title":"Trientine With Chemotherapy Dose Level 4 (1200mg)"},{"description":"trientine dihydrochloride: trientine dihydrochloride 1500MG/CAPSUE PO daily pegylated liposomal doxorubicin: pegylated liposomal doxorubicin 40mg/m2 IV D1 carboplatin: carboplatin AUC 4 IV D1","id":"OG004","title":"Trientine With Chemotherapy Dose Level 5 (1500mg)"},{"description":"trientine dihydrochloride: trientine dihydrochloride 1800MG/CAPSUE PO daily pegylated liposomal doxorubicin: pegylated liposomal doxorubicin 40mg/m2 IV D1 carboplatin: carboplatin AUC 4 IV D1","id":"OG005","title":"Trientine With Chemotherapy Dose Level 6 (1800mg)"}],"paramType":"MEDIAN","reportingStatus":"POSTED","timeFrame":"0, 10mins, 30mins, 60mins, 90mins, 120mins, 4h, 6h, 24h, 148h, 150h, 153h, 156h post 1st dose of trientine","title":"Maximum Plasma Concentration [Cmax] of Trientine","type":"SECONDARY","unitOfMeasure":"mg/L"}