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Two patients did not started phase I protocol defined therapy and were not counted as at risk.","eventGroups":[{"deathsNumAffected":5,"deathsNumAtRisk":12,"description":"Patients receive ribociclib PO QD on days 1-21 of course 1 and subsequent courses and days 2-21 of course 2 at 120 mg/m2/day, and everolimus PO QD on days 3-28 of course 1 and days 1-28 of subsequent courses at 1.2 mg/m2/day","id":"EG000","otherNumAffected":12,"otherNumAtRisk":12,"seriousNumAffected":6,"seriousNumAtRisk":12,"title":"Phase I, Dose Level 1"},{"deathsNumAffected":0,"deathsNumAtRisk":3,"description":"Patients receive ribociclib PO QD on days 1-21 of course 1 and subsequent courses and days 2-21 of course 2 at 170 mg/m2/day, and everolimus PO QD on days 3-28 of course 1 and days 1-28 of subsequent courses at 1.2 mg/m2/day","id":"EG001","otherNumAffected":3,"otherNumAtRisk":3,"seriousNumAffected":1,"seriousNumAtRisk":3,"title":"Phase I, Dose Level 2"},{"deathsNumAffected":0,"deathsNumAtRisk":5,"description":"Patients who are undergoing surgery also received ribociclib PO QD on days 7-10 at 120 mg/m2/day before surgery. Eligible patients were subsequently treated on Phase 1, Dose Level 1.","id":"EG002","otherNumAffected":5,"otherNumAtRisk":5,"seriousNumAffected":1,"seriousNumAtRisk":5,"title":"Surgical"}],"frequencyThreshold":"5","otherEvents":[{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Blood and lymphatic system disorders","sourceVocabulary":"CTCAE (5.0)","stats":[{"groupId":"EG000","numAffected":4,"numAtRisk":12,"numEvents":6},{"groupId":"EG001","numAffected":1,"numAtRisk":3,"numEvents":11},{"groupId":"EG002","numAffected":4,"numAtRisk":5,"numEvents":8}],"term":"Anemia"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Eye disorders","sourceVocabulary":"CTCAE (5.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":12,"numEvents":0},{"groupId":"EG001","numAffected":1,"numAtRisk":3,"numEvents":1},{"groupId":"EG002","numAffected":0,"numAtRisk":5,"numEvents":0}],"term":"Corneal ulcer"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Gastrointestinal 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