{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"0","upperLimit":"0","value":"0"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"17"}],"units":"Participants"}],"description":"A responder is defined as a patient who achieves a best response of partial response or complete response on the study. Response rates will be calculated as the percent of evaluable patients who are responders. The revised Response Evaluation Criteria in Solid Tumors (RECIST) guideline (version 1.1) was used to determine response and progression in this study, with specific criteria outlined for the different subtypes of tumors (e.g., 2-dimensional measurements for central nervous system (CNS) tumors).","dispersionType":"90% Confidence Interval","groups":[{"description":"Patients receive samotolisib PO BID on days 1-28. Treatment repeats every 28 days for up to 6 cycles in the absence of disease progression or unexpected toxicity. Patients undergo an x-ray, CT, MRI, FDG-PET, and blood sample collection on study.","id":"OG000","title":"Treatment (Samotolisib)"}],"paramType":"NUMBER","populationDescription":"One patient did not receive any protocol treatment and is excluded from this analysis.","reportingStatus":"POSTED","timeFrame":"Up to 2 years from study entry","title":"Objective Response Rate","type":"PRIMARY","unitOfMeasure":"percentage of patients"}