{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"10","upperLimit":"18","value":"12"},{"groupId":"OG001","lowerLimit":"10","upperLimit":"60","value":"11"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"60"},{"groupId":"OG001","value":"60"}],"units":"Participants"}],"description":"Number of days needed to achieve hematologic engraftment after high-dose chemotherapy induced myelosuppression is defined as the first day of neutrophils rising again above 0.5 G/l, and of platelets rising again above 20 G/L in the absence of platelet transfusions in the previous 3 days.","dispersionType":"Inter-Quartile Range","groups":[{"description":"Melphalan 100mg/m2/day iv days -2 and -1\n\nMelphalan: High-dose chemotherapy regimen for conditioning treatment before autologous stem cell Transplantation. Patients will receive melphalan at a total dose of 200mg/m2, divided in two doses of 100mg/m2/day on days -2 and -1, with the ASCT at day 0.","id":"OG000","title":"Arm A (Mel)"},{"description":"Melphalan 100mg/m2/day iv days -2 and -1 Bendamustine 200mg/m2/day iv days -4 and -3\n\nMelphalan: High-dose chemotherapy regimen for conditioning treatment before autologous stem cell Transplantation. Patients will receive melphalan at a total dose of 200mg/m2, divided in two doses of 100mg/m2/day on days -2 and -1, with the ASCT at day 0.\n\nBendamustine: High-dose chemotherapy regimen for conditioning treatment before autologous stem cell Transplantation. Patients will receive bendamustine at a total dose of 400mg/m2, divided in two doses of 200mg/m2/day on days -4 and -3. Melphalan is given at a total dose of 200mg/m2, divided in two doses of 100mg/m2/day, each on days -2 and -1, with the ASCT at day 0.","id":"OG001","title":"Arm B (BenMel)"}],"paramType":"MEDIAN","populationDescription":"Time to neutrophil engraftment was defined as the duration between day 0 and the first 3 days of neutrophils \\>0.5 × 109/L after ASCT.","reportingStatus":"POSTED","timeFrame":"30 days","title":"Hematologic Engraftment After High-dose Chemotherapy","type":"SECONDARY","unitOfMeasure":"days"}