{"analyses":[{"groupDescription":"Week 5","groupIds":["OG000","OG002"],"nonInferiorityType":"SUPERIORITY","pValue":"0.41","pValueComment":"One-sided significance level 0.05","statisticalMethod":"t-test, 1 sided"},{"groupDescription":"Week 5","groupIds":["OG001","OG002"],"nonInferiorityType":"SUPERIORITY","pValue":"0.60","pValueComment":"One-sided significance level 0.05","statisticalMethod":"t-test, 1 sided"},{"groupDescription":"Week 9","groupIds":["OG000","OG002"],"nonInferiorityType":"SUPERIORITY","pValue":"0.90","pValueComment":"One-sided significance level 0.05","statisticalMethod":"t-test, 1 sided"},{"groupDescription":"Week 9","groupIds":["OG001","OG002"],"nonInferiorityType":"SUPERIORITY","pValue":"0.79","pValueComment":"One-sided significance level 0.05","statisticalMethod":"t-test, 1 sided"}],"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"7.27","value":"3.35"},{"groupId":"OG001","spread":"5.82","value":"2.81"},{"groupId":"OG002","spread":"6.00","value":"3.08"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"65"},{"groupId":"OG001","value":"59"},{"groupId":"OG002","value":"61"}],"units":"Participants"}],"title":"Week 5"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"6.51","value":"2.05"},{"groupId":"OG001","spread":"4.72","value":"2.72"},{"groupId":"OG002","spread":"6.93","value":"3.58"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"65"},{"groupId":"OG001","value":"60"},{"groupId":"OG002","value":"60"}],"units":"Participants"}],"title":"Week 9"}],"denoms":[{"counts":[{"groupId":"OG000","value":"79"},{"groupId":"OG001","value":"74"},{"groupId":"OG002","value":"76"}],"units":"Participants"}],"description":"The PROMIS Global Satisfaction with Sex Life subscore measures self-reported global satisfaction, interest, and interference in sexual health over the past 7 days. Possible scores range from 3 to 30, with higher scores indicating more satisfaction with sex life. Change score is calculated by subtracting baseline from later score, with a positive change score indicating increased satisfaction. This score is referred to as the \"PROMIS sexual desire and satisfaction measure\" in the protocol.","dispersionType":"Standard Deviation","groups":[{"description":"One Bupropion 150 mg XL capsule PO in a.m. daily for one week; one Bupropion 150 mg XL capsule and one placebo capsule PO in a.m. daily for 8 weeks; one placebo capsule daily PO in a.m. for one 1 week (titration off).","id":"OG000","title":"Bupropion 150 mg"},{"description":"One Bupropion 150 mg XL capsule PO in a.m. daily for one week; two Bupropion 150 mg XL capsules PO in a.m. daily for 8 weeks (300 mg target dose); one Bupropion 150 mg XL capsule PO in a.m. daily for 1 week (titration off)","id":"OG001","title":"Bupropion 300 mg"},{"description":"One placebo capsule PO in a.m. daily for 1 week; two placebo capsules PO in a.m. daily for 8 weeks; one placebo capsule PO in a.m. daily for 1 week (titration off)","id":"OG002","title":"Placebo"}],"paramType":"MEAN","populationDescription":"Eligible with baseline data","reportingStatus":"POSTED","timeFrame":"Baseline (prior to randomization) and 5 and 9 weeks from start of study treatment (within 21 days of randomization)","title":"Change From Baseline in the PROMIS Global Satisfaction With Sex Life Subscore of Sexual Function and Satisfaction Measure (\"Sexual Desire and Satisfaction\")","type":"SECONDARY","unitOfMeasure":"units on a scale"}