{"analyses":[{"groupIds":["OG000","OG002"],"nonInferiorityType":"SUPERIORITY","pValue":"0.24","pValueComment":"One-side significance level 0.05","statisticalMethod":"t-test, 1 sided"},{"groupIds":["OG000","OG002"],"nonInferiorityType":"SUPERIORITY","pValue":"0.74","pValueComment":"One-sided significance level 0.05","statisticalMethod":"t-test, 1 sided"}],"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.90","value":"0.70"},{"groupId":"OG001","spread":"0.69","value":"0.48"},{"groupId":"OG002","spread":"0.99","value":"0.58"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"66"},{"groupId":"OG001","value":"61"},{"groupId":"OG002","value":"63"}],"units":"Participants"}],"description":"The desire subscore of the female sexual function index (FSFI) measures self-reported sexual desire. Possible scores range from 1.2 to 6, with higher scores indicating increased desire. Change score is calculated by subtracting baseline from later score, with a positive change score indicating increased desire. This measure is referred to as \"sexual desire\" in the protocol.","dispersionType":"Standard Deviation","groups":[{"description":"One Bupropion 150 mg XL capsule PO in a.m. daily for one week; one Bupropion 150 mg XL capsule and one placebo capsule PO in a.m. daily for 8 weeks; one placebo capsule daily PO in a.m. for one 1 week (titration off).","id":"OG000","title":"Bupropion 150 mg"},{"description":"One Bupropion 150 mg XL capsule PO in a.m. daily for one week; two Bupropion 150 mg XL capsules PO in a.m. daily for 8 weeks (300 mg target dose); one Bupropion 150 mg XL capsule PO in a.m. daily for 1 week (titration off)","id":"OG001","title":"Bupropion 300 mg"},{"description":"One placebo capsule PO in a.m. daily for 1 week; two placebo capsules PO in a.m. daily for 8 weeks; one placebo capsule PO in a.m. daily for 1 week (titration off)","id":"OG002","title":"Placebo"}],"paramType":"MEAN","populationDescription":"Eligible with baseline and 5 week data","reportingStatus":"POSTED","timeFrame":"Baseline (prior to randomization) and 5 weeks from start of study treatment (within 21 days of randomization)","title":"Change From Baseline at 5 Weeks in Desire Subscore of the FSFI (\"Sexual Desire\")","type":"SECONDARY","unitOfMeasure":"units on a scale"}