{"eventGroups":[{"deathsNumAffected":2,"deathsNumAtRisk":3,"description":"Lorlatinib will be given orally once daily continuously for 28 days. The dose level of lorlatinib will be 45 mg/m2/dose. Patients must be under 18 years of age at time of enrollment.\n\nLorlatinib: Lorlatinib will be given orally once daily continuously in 28-day cycles. Lorlatinib will be provided as 5 mg or 25 mg tablets.","id":"EG000","otherNumAffected":3,"otherNumAtRisk":3,"seriousNumAffected":1,"seriousNumAtRisk":3,"title":"Cohort A1 DL1"},{"deathsNumAffected":3,"deathsNumAtRisk":3,"description":"Lorlatinib will be given orally once daily continuously for 28 days. The dose level of lorlatinib will be 60 mg/m2/dose. Patients must be under 18 years of age at time of enrollment.\n\nLorlatinib: Lorlatinib will be given orally once daily continuously in 28-day cycles. Lorlatinib will be provided as 5 mg or 25 mg tablets.","id":"EG001","otherNumAffected":3,"otherNumAtRisk":3,"seriousNumAffected":1,"seriousNumAtRisk":3,"title":"Cohort A1 DL2"},{"deathsNumAffected":2,"deathsNumAtRisk":3,"description":"Lorlatinib will be given orally once daily continuously for 28 days. The dose level of lorlatinib will be 75 mg/m2/dose. Patients must be under 18 years of age at time of enrollment.\n\nLorlatinib: Lorlatinib will be given orally once daily continuously in 28-day cycles. Lorlatinib will be provided as 5 mg or 25 mg tablets.","id":"EG002","otherNumAffected":3,"otherNumAtRisk":3,"seriousNumAffected":0,"seriousNumAtRisk":3,"title":"Cohort A1 DL3"},{"deathsNumAffected":9,"deathsNumAtRisk":10,"description":"Lorlatinib will be given orally once daily continuously for 28 days. The dose level of lorlatinib will be 95 mg/m2/dose. Patients must be under 18 years of age at time of enrollment.\n\nLorlatinib: Lorlatinib will be given orally once daily continuously in 28-day cycles. Lorlatinib will be provided as 5 mg or 25 mg tablets.","id":"EG003","otherNumAffected":9,"otherNumAtRisk":10,"seriousNumAffected":3,"seriousNumAtRisk":10,"title":"Cohort A1 DL4"},{"deathsNumAffected":3,"deathsNumAtRisk":6,"description":"Lorlatinib will be given orally once daily continuously for 28 days. The dose level of lorlatinib will be 115 mg/m2/dose. Patients must be under 18 years of age at time of enrollment.\n\nLorlatinib: Lorlatinib will be given orally once daily continuously in 28-day cycles. Lorlatinib will be provided as 5 mg or 25 mg tablets.","id":"EG004","otherNumAffected":6,"otherNumAtRisk":6,"seriousNumAffected":2,"seriousNumAtRisk":6,"title":"Cohort A1 DL5"},{"deathsNumAffected":4,"deathsNumAtRisk":6,"description":"Lorlatinib will be given at 100 mg orally once daily continuously for 28 days. Patients must be 18 years of age or older at time of enrollment.\n\nLorlatinib: Lorlatinib will be given orally once daily continuously in 28-day cycles. Lorlatinib will be provided as 5 mg or 25 mg tablets.","id":"EG005","otherNumAffected":6,"otherNumAtRisk":6,"seriousNumAffected":4,"seriousNumAtRisk":6,"title":"Cohort A2 DL 3A"},{"deathsNumAffected":2,"deathsNumAtRisk":6,"description":"Lorlatinib will be given at 150 mg orally once daily continuously for 28 days. Patients must be 18 years of age or older at time of enrollment.\n\nLorlatinib: Lorlatinib will be given orally once daily continuously in 28-day cycles. Lorlatinib will be provided as 5 mg or 25 mg tablets.","id":"EG006","otherNumAffected":6,"otherNumAtRisk":6,"seriousNumAffected":3,"seriousNumAtRisk":6,"title":"Cohort A2 DL4A"},{"deathsNumAffected":0,"deathsNumAtRisk":4,"description":"Lorlatinib will be given at 150 mg orally once daily continuously for 28 days. Patients must be 18 years of age or older at time of enrollment.\n\nLorlatinib: Lorlatinib will be given orally once daily continuously in 28-day cycles. Lorlatinib will be provided as 5 mg or 25 mg tablets.","id":"EG007","otherNumAffected":4,"otherNumAtRisk":4,"seriousNumAffected":1,"seriousNumAtRisk":4,"title":"Cohort A2 DL4A Expansion"},{"deathsNumAffected":3,"deathsNumAtRisk":5,"description":"Lorlatinib will be given orally once daily continuously for 28 days. The dose level of lorlatinib will be 115 mg/m2/dose. Patients must be under 18 years of age at time of enrollment.\n\nLorlatinib: Lorlatinib will be given orally once daily continuously in 28-day cycles. Lorlatinib will be provided as 5 mg or 25 mg tablets.","id":"EG008","otherNumAffected":5,"otherNumAtRisk":5,"seriousNumAffected":3,"seriousNumAtRisk":5,"title":"Cohort B1 DL5"},{"deathsNumAffected":2,"deathsNumAtRisk":3,"description":"Lorlatinib will be given orally once daily continuously for 28 days at 95mg/m2/dose. Lorlatinib should be administered at least one hour prior to conventional chemotherapy (Cyclophosphamide and Topotecan) on days 1-5 of each cycle. Patients must be under 18 years of age at time of enrollment.\n\nLorlatinib: Lorlatinib will be given orally once daily continuously in 28-day cycles. Lorlatinib will be provided as 5 mg or 25 mg tablets.\n\nCyclophosphamide: Cyclophosphamide 250mg/m2/day will be administered as a 30 minute IV infusion on days 1-5 of each cycle\n\nTopotecan: Topotecan 0.75mg/m2/day will be administered as a 30 minute IV infusion immediately following cyclophosphamide on days 1-5 of each cycle\n\nFilgrastim/pegfilgrastim: Filgrastim is to be given with each course beginning 24-48 hours following completion of cyclophosphamide and topotecan and continued through post-nadir count recovery with an ANC \\> 2000/mm\\^3 at 5mcg/kg/day. Filgrastim must be discontinued at least 24 hours prior to the start of the next course of therapy.\n\nPegfilgrastim (100mcg/kg; 6mg maximum dose) may be substituted and is given one time at 24-48 hours from completion of cyclophosphamide and topotecan.","id":"EG009","otherNumAffected":3,"otherNumAtRisk":3,"seriousNumAffected":3,"seriousNumAtRisk":3,"title":"Cohort B2 DL4B"},{"deathsNumAffected":7,"deathsNumAtRisk":13,"description":"Lorlatinib will be given orally once daily continuously for 28 days at 115mg/m2/dose. Lorlatinib should be administered at least one hour prior to conventional chemotherapy (Cyclophosphamide and Topotecan) on days 1-5 of each cycle. Patients must be under 18 years of age at time of enrollment.\n\nLorlatinib: Lorlatinib will be given orally once daily continuously in 28-day cycles. Lorlatinib will be provided as 5 mg or 25 mg tablets.\n\nCyclophosphamide: Cyclophosphamide 250mg/m2/day will be administered as a 30 minute IV infusion on days 1-5 of each cycle\n\nTopotecan: Topotecan 0.75mg/m2/day will be administered as a 30 minute IV infusion immediately following cyclophosphamide on days 1-5 of each cycle\n\nFilgrastim/pegfilgrastim: Filgrastim is to be given with each course beginning 24-48 hours following completion of cyclophosphamide and topotecan and continued through post-nadir count recovery with an ANC \\> 2000/mm\\^3 at 5mcg/kg/day. Filgrastim must be discontinued at least 24 hours prior to the start of the next course of therapy.\n\nPegfilgrastim (100mcg/kg; 6mg maximum dose) may be substituted and is given one time at 24-48 hours from completion of cyclophosphamide and topotecan.","id":"EG010","otherNumAffected":12,"otherNumAtRisk":13,"seriousNumAffected":10,"seriousNumAtRisk":13,"title":"Cohort B2 DL5B"},{"deathsNumAffected":0,"deathsNumAtRisk":1,"description":"Lorlatinib will be given orally once daily continuously for 28 days at 100mg/day. Lorlatinib should be administered at least one hour prior to conventional chemotherapy (Cyclophosphamide and Topotecan) on days 1-5 of each cycle. Patients must be 18 years of age or older at time of enrollment.\n\nLorlatinib: Lorlatinib will be given orally once daily continuously in 28-day cycles. Lorlatinib will be provided as 5 mg or 25 mg tablets.\n\nCyclophosphamide: Cyclophosphamide 250mg/m2/day will be administered as a 30 minute IV infusion on days 1-5 of each cycle\n\nTopotecan: Topotecan 0.75mg/m2/day will be administered as a 30 minute IV infusion immediately following cyclophosphamide on days 1-5 of each cycle\n\nFilgrastim/pegfilgrastim: Filgrastim is to be given with each course beginning 24-48 hours following completion of cyclophosphamide and topotecan and continued through post-nadir count recovery with an ANC \\> 2000/mm\\^3 at 5mcg/kg/day. Filgrastim must be discontinued at least 24 hours prior to the start of the next course of therapy.\n\nPegfilgrastim (100mcg/kg; 6mg maximum dose) may be substituted and is given one time at 24-48 hours from completion of cyclophosphamide and topotecan.","id":"EG011","otherNumAffected":1,"otherNumAtRisk":1,"seriousNumAffected":1,"seriousNumAtRisk":1,"title":"Cohort B2 DL3A"},{"deathsNumAffected":0,"deathsNumAtRisk":1,"description":"Lorlatinib will be given orally once daily continuously for 28 days at 150mg/day. Lorlatinib should be administered at least one hour prior to conventional chemotherapy (Cyclophosphamide and Topotecan) on days 1-5 of each cycle. Patients must be 18 years of age or older at time of enrollment.\n\nLorlatinib: Lorlatinib will be given orally once daily continuously in 28-day cycles. Lorlatinib will be provided as 5 mg or 25 mg tablets.\n\nCyclophosphamide: Cyclophosphamide 250mg/m2/day will be administered as a 30 minute IV infusion on days 1-5 of each cycle\n\nTopotecan: Topotecan 0.75mg/m2/day will be administered as a 30 minute IV infusion immediately following cyclophosphamide on days 1-5 of each cycle\n\nFilgrastim/pegfilgrastim: Filgrastim is to be given with each course beginning 24-48 hours following completion of cyclophosphamide and topotecan and continued through post-nadir count recovery with an ANC \\> 2000/mm\\^3 at 5mcg/kg/day. Filgrastim must be discontinued at least 24 hours prior to the start of the next course of therapy.\n\nPegfilgrastim (100mcg/kg; 6mg maximum dose) may be substituted and is given one time at 24-48 hours from completion of cyclophosphamide and topotecan.","id":"EG012","otherNumAffected":1,"otherNumAtRisk":1,"seriousNumAffected":1,"seriousNumAtRisk":1,"title":"Cohort B2 DL4A"}],"frequencyThreshold":"5","otherEvents":[{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Blood and lymphatic system disorders","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":3},{"groupId":"EG001","numAffected":3,"numAtRisk":3},{"groupId":"EG002","numAffected":1,"numAtRisk":3},{"groupId":"EG003","numAffected":7,"numAtRisk":10},{"groupId":"EG004","numAffected":3,"numAtRisk":6},{"groupId":"EG005","numAffected":4,"numAtRisk":6},{"groupId":"EG006","numAffected":4,"numAtRisk":6},{"groupId":"EG007","numAffected":2,"numAtRisk":4},{"groupId":"EG008","numAffected":3,"numAtRisk":5},{"groupId":"EG009","numAffected":3,"numAtRisk":3},{"groupId":"EG010","numAffected":12,"numAtRisk":13},{"groupId":"EG011","numAffected":1,"numAtRisk":1},{"groupId":"EG012","numAffected":1,"numAtRisk":1}],"term":"Anemia"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Blood and lymphatic system disorders","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3},{"groupId":"EG001","numAffected":0,"numAtRisk":3},{"groupId":"EG002","numAffected":0,"numAtRisk":3},{"groupId":"EG003","numAffected":0,"numAtRisk":10},{"groupId":"EG004","numAffected":0,"numAtRisk":6},{"groupId":"EG005","numAffected":0,"numAtRisk":6},{"groupId":"EG006","numAffected":0,"numAtRisk":6},{"groupId":"EG007","numAffected":1,"numAtRisk":4},{"groupId":"EG008","numAffected":0,"numAtRisk":5},{"groupId":"EG009","numAffected":0,"numAtRisk":3},{"groupId":"EG010","numAffected":1,"numAtRisk":13},{"groupId":"EG011","numAffected":1,"numAtRisk":1},{"groupId":"EG012","numAffected":0,"numAtRisk":1}],"term":"Leukocytosis"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Cardiac disorders","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3},{"groupId":"EG001","numAffected":0,"numAtRisk":3},{"groupId":"EG002","numAffected":0,"numAtRisk":3},{"groupId":"EG003","numAffected":0,"numAtRisk":10},{"groupId":"EG004","numAffected":0,"numAtRisk":6},{"groupId":"EG005","numAffected":0,"numAtRisk":6},{"groupId":"EG006","numAffected":1,"numAtRisk":6},{"groupId":"EG007","numAffected":0,"numAtRisk":4},{"groupId":"EG008","numAffected":0,"numAtRisk":5},{"groupId":"EG009","numAffected":0,"numAtRisk":3},{"groupId":"EG010","numAffected":1,"numAtRisk":13},{"groupId":"EG011","numAffected":0,"numAtRisk":1},{"groupId":"EG012","numAffected":0,"numAtRisk":1}],"term":"Atrioventricular block first degree"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Cardiac disorders","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3},{"groupId":"EG001","numAffected":0,"numAtRisk":3},{"groupId":"EG002","numAffected":0,"numAtRisk":3},{"groupId":"EG003","numAffected":1,"numAtRisk":10},{"groupId":"EG004","numAffected":0,"numAtRisk":6},{"groupId":"EG005","numAffected":0,"numAtRisk":6},{"groupId":"EG006","numAffected":0,"numAtRisk":6},{"groupId":"EG007","numAffected":0,"numAtRisk":4},{"groupId":"EG008","numAffected":0,"numAtRisk":5},{"groupId":"EG009","numAffected":0,"numAtRisk":3},{"groupId":"EG010","numAffected":0,"numAtRisk":13},{"groupId":"EG011","numAffected":0,"numAtRisk":1},{"groupId":"EG012","numAffected":0,"numAtRisk":1}],"term":"Palpitations"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Cardiac disorders","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3},{"groupId":"EG001","numAffected":0,"numAtRisk":3},{"groupId":"EG002","numAffected":0,"numAtRisk":3},{"groupId":"EG003","numAffected":0,"numAtRisk":10},{"groupId":"EG004","numAffected":0,"numAtRisk":6},{"groupId":"EG005","numAffected":0,"numAtRisk":6},{"groupId":"EG006","numAffected":1,"numAtRisk":6},{"groupId":"EG007","numAffected":0,"numAtRisk":4},{"groupId":"EG008","numAffected":0,"numAtRisk":5},{"groupId":"EG009","numAffected":0,"numAtRisk":3},{"groupId":"EG010","numAffected":0,"numAtRisk":13},{"groupId":"EG011","numAffected":0,"numAtRisk":1},{"groupId":"EG012","numAffected":0,"numAtRisk":1}],"term":"Sinus bradycardia"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Cardiac disorders","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3},{"groupId":"EG001","numAffected":1,"numAtRisk":3},{"groupId":"EG002","numAffected":0,"numAtRisk":3},{"groupId":"EG003","numAffected":2,"numAtRisk":10},{"groupId":"EG004","numAffected":0,"numAtRisk":6},{"groupId":"EG005","numAffected":2,"numAtRisk":6},{"groupId":"EG006","numAffected":1,"numAtRisk":6},{"groupId":"EG007","numAffected":0,"numAtRisk":4},{"groupId":"EG008","numAffected":2,"numAtRisk":5},{"groupId":"EG009","numAffected":1,"numAtRisk":3},{"groupId":"EG010","numAffected":5,"numAtRisk":13},{"groupId":"EG011","numAffected":0,"numAtRisk":1},{"groupId":"EG012","numAffected":0,"numAtRisk":1}],"term":"Sinus tachycardia"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Ear and labyrinth disorders","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3},{"groupId":"EG001","numAffected":0,"numAtRisk":3},{"groupId":"EG002","numAffected":0,"numAtRisk":3},{"groupId":"EG003","numAffected":2,"numAtRisk":10},{"groupId":"EG004","numAffected":0,"numAtRisk":6},{"groupId":"EG005","numAffected":0,"numAtRisk":6},{"groupId":"EG006","numAffected":0,"numAtRisk":6},{"groupId":"EG007","numAffected":0,"numAtRisk":4},{"groupId":"EG008","numAffected":0,"numAtRisk":5},{"groupId":"EG009","numAffected":1,"numAtRisk":3},{"groupId":"EG010","numAffected":1,"numAtRisk":13},{"groupId":"EG011","numAffected":1,"numAtRisk":1},{"groupId":"EG012","numAffected":1,"numAtRisk":1}],"term":"Ear pain"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Ear and labyrinth disorders","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3},{"groupId":"EG001","numAffected":0,"numAtRisk":3},{"groupId":"EG002","numAffected":1,"numAtRisk":3},{"groupId":"EG003","numAffected":0,"numAtRisk":10},{"groupId":"EG004","numAffected":1,"numAtRisk":6},{"groupId":"EG005","numAffected":0,"numAtRisk":6},{"groupId":"EG006","numAffected":0,"numAtRisk":6},{"groupId":"EG007","numAffected":1,"numAtRisk":4},{"groupId":"EG008","numAffected":0,"numAtRisk":5},{"groupId":"EG009","numAffected":0,"numAtRisk":3},{"groupId":"EG010","numAffected":0,"numAtRisk":13},{"groupId":"EG011","numAffected":0,"numAtRisk":1},{"groupId":"EG012","numAffected":0,"numAtRisk":1}],"term":"Hearing impaired"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Ear and labyrinth disorders","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3},{"groupId":"EG001","numAffected":0,"numAtRisk":3},{"groupId":"EG002","numAffected":0,"numAtRisk":3},{"groupId":"EG003","numAffected":0,"numAtRisk":10},{"groupId":"EG004","numAffected":2,"numAtRisk":6},{"groupId":"EG005","numAffected":0,"numAtRisk":6},{"groupId":"EG006","numAffected":2,"numAtRisk":6},{"groupId":"EG007","numAffected":1,"numAtRisk":4},{"groupId":"EG008","numAffected":1,"numAtRisk":5},{"groupId":"EG009","numAffected":0,"numAtRisk":3},{"groupId":"EG010","numAffected":0,"numAtRisk":13},{"groupId":"EG011","numAffected":1,"numAtRisk":1},{"groupId":"EG012","numAffected":0,"numAtRisk":1}],"term":"Tinnitus"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Endocrine disorders","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3},{"groupId":"EG001","numAffected":0,"numAtRisk":3},{"groupId":"EG002","numAffected":0,"numAtRisk":3},{"groupId":"EG003","numAffected":0,"numAtRisk":10},{"groupId":"EG004","numAffected":1,"numAtRisk":6},{"groupId":"EG005","numAffected":1,"numAtRisk":6},{"groupId":"EG006","numAffected":0,"numAtRisk":6},{"groupId":"EG007","numAffected":0,"numAtRisk":4},{"groupId":"EG008","numAffected":0,"numAtRisk":5},{"groupId":"EG009","numAffected":0,"numAtRisk":3},{"groupId":"EG010","numAffected":0,"numAtRisk":13},{"groupId":"EG011","numAffected":0,"numAtRisk":1},{"groupId":"EG012","numAffected":0,"numAtRisk":1}],"term":"Hypothyroidism"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Eye disorders","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3},{"groupId":"EG001","numAffected":0,"numAtRisk":3},{"groupId":"EG002","numAffected":0,"numAtRisk":3},{"groupId":"EG003","numAffected":0,"numAtRisk":10},{"groupId":"EG004","numAffected":1,"numAtRisk":6},{"groupId":"EG005","numAffected":0,"numAtRisk":6},{"groupId":"EG006","numAffected":0,"numAtRisk":6},{"groupId":"EG007","numAffected":0,"numAtRisk":4},{"groupId":"EG008","numAffected":1,"numAtRisk":5},{"groupId":"EG009","numAffected":0,"numAtRisk":3},{"groupId":"EG010","numAffected":1,"numAtRisk":13},{"groupId":"EG011","numAffected":1,"numAtRisk":1},{"groupId":"EG012","numAffected":0,"numAtRisk":1}],"term":"ABNORMAL EYE MOVEMENTS"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Eye disorders","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3},{"groupId":"EG001","numAffected":0,"numAtRisk":3},{"groupId":"EG002","numAffected":0,"numAtRisk":3},{"groupId":"EG003","numAffected":0,"numAtRisk":10},{"groupId":"EG004","numAffected":0,"numAtRisk":6},{"groupId":"EG005","numAffected":0,"numAtRisk":6},{"groupId":"EG006","numAffected":1,"numAtRisk":6},{"groupId":"EG007","numAffected":0,"numAtRisk":4},{"groupId":"EG008","numAffected":0,"numAtRisk":5},{"groupId":"EG009","numAffected":0,"numAtRisk":3},{"groupId":"EG010","numAffected":1,"numAtRisk":13},{"groupId":"EG011","numAffected":0,"numAtRisk":1},{"groupId":"EG012","numAffected":0,"numAtRisk":1}],"term":"Blurred vision"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Eye disorders","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3},{"groupId":"EG001","numAffected":0,"numAtRisk":3},{"groupId":"EG002","numAffected":0,"numAtRisk":3},{"groupId":"EG003","numAffected":0,"numAtRisk":10},{"groupId":"EG004","numAffected":0,"numAtRisk":6},{"groupId":"EG005","numAffected":1,"numAtRisk":6},{"groupId":"EG006","numAffected":0,"numAtRisk":6},{"groupId":"EG007","numAffected":0,"numAtRisk":4},{"groupId":"EG008","numAffected":0,"numAtRisk":5},{"groupId":"EG009","numAffected":0,"numAtRisk":3},{"groupId":"EG010","numAffected":0,"numAtRisk":13},{"groupId":"EG011","numAffected":1,"numAtRisk":1},{"groupId":"EG012","numAffected":0,"numAtRisk":1}],"term":"Conjunctivitis"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Eye disorders","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3},{"groupId":"EG001","numAffected":0,"numAtRisk":3},{"groupId":"EG002","numAffected":0,"numAtRisk":3},{"groupId":"EG003","numAffected":0,"numAtRisk":10},{"groupId":"EG004","numAffected":0,"numAtRisk":6},{"groupId":"EG005","numAffected":0,"numAtRisk":6},{"groupId":"EG006","numAffected":0,"numAtRisk":6},{"groupId":"EG007","numAffected":0,"numAtRisk":4},{"groupId":"EG008","numAffected":0,"numAtRisk":5},{"groupId":"EG009","numAffected":1,"numAtRisk":3},{"groupId":"EG010","numAffected":0,"numAtRisk":13},{"groupId":"EG011","numAffected":0,"numAtRisk":1},{"groupId":"EG012","numAffected":0,"numAtRisk":1}],"term":"Dry eye"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Eye disorders","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3},{"groupId":"EG001","numAffected":0,"numAtRisk":3},{"groupId":"EG002","numAffected":0,"numAtRisk":3},{"groupId":"EG003","numAffected":0,"numAtRisk":10},{"groupId":"EG004","numAffected":0,"numAtRisk":6},{"groupId":"EG005","numAffected":1,"numAtRisk":6},{"groupId":"EG006","numAffected":0,"numAtRisk":6},{"groupId":"EG007","numAffected":0,"numAtRisk":4},{"groupId":"EG008","numAffected":0,"numAtRisk":5},{"groupId":"EG009","numAffected":0,"numAtRisk":3},{"groupId":"EG010","numAffected":0,"numAtRisk":13},{"groupId":"EG011","numAffected":0,"numAtRisk":1},{"groupId":"EG012","numAffected":0,"numAtRisk":1}],"term":"Eye pain"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Eye disorders","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3},{"groupId":"EG001","numAffected":1,"numAtRisk":3},{"groupId":"EG002","numAffected":0,"numAtRisk":3},{"groupId":"EG003","numAffected":0,"numAtRisk":10},{"groupId":"EG004","numAffected":0,"numAtRisk":6},{"groupId":"EG005","numAffected":0,"numAtRisk":6},{"groupId":"EG006","numAffected":0,"numAtRisk":6},{"groupId":"EG007","numAffected":0,"numAtRisk":4},{"groupId":"EG008","numAffected":0,"numAtRisk":5},{"groupId":"EG009","numAffected":0,"numAtRisk":3},{"groupId":"EG010","numAffected":0,"numAtRisk":13},{"groupId":"EG011","numAffected":0,"numAtRisk":1},{"groupId":"EG012","numAffected":0,"numAtRisk":1}],"term":"Eyelid function disorder"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Eye disorders","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3},{"groupId":"EG001","numAffected":0,"numAtRisk":3},{"groupId":"EG002","numAffected":0,"numAtRisk":3},{"groupId":"EG003","numAffected":0,"numAtRisk":10},{"groupId":"EG004","numAffected":0,"numAtRisk":6},{"groupId":"EG005","numAffected":0,"numAtRisk":6},{"groupId":"EG006","numAffected":0,"numAtRisk":6},{"groupId":"EG007","numAffected":0,"numAtRisk":4},{"groupId":"EG008","numAffected":0,"numAtRisk":5},{"groupId":"EG009","numAffected":0,"numAtRisk":3},{"groupId":"EG010","numAffected":0,"numAtRisk":13},{"groupId":"EG011","numAffected":1,"numAtRisk":1},{"groupId":"EG012","numAffected":0,"numAtRisk":1}],"term":"Keratitis"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Eye 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