{"denoms":[{"counts":[{"groupId":"BG000","value":"329"},{"groupId":"BG001","value":"328"},{"groupId":"BG002","value":"330"},{"groupId":"BG003","value":"987"}],"units":"Participants"}],"groups":[{"description":"During Chemotherapy:\n\nPatients received durvalumab (D) 1500 mg in combination with tremelimumab (T) 75 mg IV infusion Q3W for 4 doses/cycles (Weeks 0, 3, 6 and 9). For chemotherapy (EP), patients received etoposide (80-100 mg/m\\^2) with either carboplatin (area under the curve 5-6) or cisplatin (75-80 mg/m\\^2) IV infusion Q3W for 4 doses/cycles (Weeks 0, 3, 6 and 9).\n\nPost-Chemotherapy:\n\nPatients then continued to receive durvalumab 1500 mg IV infusion Q4W from Week 12 until PD, unless there was unacceptable toxicity, withdrawal of consent, or another discontinuation criterion was met. Patients also received an additional dose of tremelimumab 75 mg IV infusion post-chemotherapy (in combination with durvalumab) at Week 16 if they completed all 4 doses of durvalumab + tremelimumab during chemotherapy.","id":"BG000","title":"All Patients: D + T + EP"},{"description":"During Chemotherapy:\n\nPatients received durvalumab (D) 1500 mg IV infusion Q3W for 4 doses/cycles (Weeks 0, 3, 6 and 9). For chemotherapy (EP), patients received etoposide (80-100 mg/m\\^2) with either carboplatin (area under the curve 5-6) or cisplatin (75-80 mg/m\\^2) IV infusion Q3W for 4 doses/cycles (Weeks 0, 3, 6 and 9).\n\nPost-Chemotherapy:\n\nPatients then continued to receive durvalumab 1500 mg IV infusion Q4W from Week 12 until PD, unless there was unacceptable toxicity, withdrawal of consent, or another discontinuation criterion was met.","id":"BG001","title":"All Patients: D + EP"},{"description":"For chemotherapy (EP), patients received etoposide (80-100 mg/m\\^2) with either carboplatin (area under the curve 5-6) or cisplatin (75-80 mg/m\\^2) IV infusion Q3W for 4 doses/cycles (Weeks 0, 3, 6 and 9). An additional 2 doses of EP (at Weeks 12 and 15) could be given at the investigators' discretion if clinically indicated.","id":"BG002","title":"All Patients: EP"},{"description":"Total of all reporting groups","id":"BG003","title":"Total"}],"measures":[{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","value":"21"},{"groupId":"BG001","value":"13"},{"groupId":"BG002","value":"28"},{"groupId":"BG003","value":"62"}],"title":"<50"},{"measurements":[{"groupId":"BG000","value":"175"},{"groupId":"BG001","value":"195"},{"groupId":"BG002","value":"169"},{"groupId":"BG003","value":"539"}],"title":"≥50 to <65"},{"measurements":[{"groupId":"BG000","value":"108"},{"groupId":"BG001","value":"98"},{"groupId":"BG002","value":"110"},{"groupId":"BG003","value":"316"}],"title":"≥65 to <75"},{"measurements":[{"groupId":"BG000","value":"25"},{"groupId":"BG001","value":"22"},{"groupId":"BG002","value":"23"},{"groupId":"BG003","value":"70"}],"title":"≥75"}],"denoms":[{"counts":[{"groupId":"BG000","value":"329"},{"groupId":"BG001","value":"328"},{"groupId":"BG002","value":"330"},{"groupId":"BG003","value":"987"}],"units":"Participants"}],"title":"Al Patients"},{"categories":[{"measurements":[{"groupId":"BG000","value":"16"},{"groupId":"BG001","value":"10"},{"groupId":"BG002","value":"20"},{"groupId":"BG003","value":"46"}],"title":"<50"},{"measurements":[{"groupId":"BG000","value":"138"},{"groupId":"BG001","value":"157"},{"groupId":"BG002","value":"137"},{"groupId":"BG003","value":"432"}],"title":"≥50 to <65"},{"measurements":[{"groupId":"BG000","value":"91"},{"groupId":"BG001","value":"82"},{"groupId":"BG002","value":"90"},{"groupId":"BG003","value":"263"}],"title":"≥65 to <75"},{"measurements":[{"groupId":"BG000","value":"23"},{"groupId":"BG001","value":"19"},{"groupId":"BG002","value":"22"},{"groupId":"BG003","value":"64"}],"title":"≥75"}],"denoms":[{"counts":[{"groupId":"BG000","value":"268"},{"groupId":"BG001","value":"268"},{"groupId":"BG002","value":"269"},{"groupId":"BG003","value":"805"}],"units":"Participants"}],"title":"Global Cohort"},{"categories":[{"measurements":[{"groupId":"BG000","value":"5"},{"groupId":"BG001","value":"3"},{"groupId":"BG002","value":"8"},{"groupId":"BG003","value":"16"}],"title":"<50"},{"measurements":[{"groupId":"BG000","value":"40"},{"groupId":"BG001","value":"39"},{"groupId":"BG002","value":"33"},{"groupId":"BG003","value":"112"}],"title":"≥50 to <65"},{"measurements":[{"groupId":"BG000","value":"17"},{"groupId":"BG001","value":"16"},{"groupId":"BG002","value":"20"},{"groupId":"BG003","value":"53"}],"title":"≥65 to <75"},{"measurements":[{"groupId":"BG000","value":"3"},{"groupId":"BG001","value":"3"},{"groupId":"BG002","value":"1"},{"groupId":"BG003","value":"7"}],"title":"≥75"}],"denoms":[{"counts":[{"groupId":"BG000","value":"65"},{"groupId":"BG001","value":"61"},{"groupId":"BG002","value":"62"},{"groupId":"BG003","value":"188"}],"units":"Participants"}],"title":"China Cohort"}],"paramType":"COUNT_OF_PARTICIPANTS","populationDescription":"Baseline data is presented for all patients, as well as separately for the global and China cohorts.","title":"Age, Customized","unitOfMeasure":"Participants"},{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","value":"74"},{"groupId":"BG001","value":"86"},{"groupId":"BG002","value":"95"},{"groupId":"BG003","value":"255"}],"title":"Female"},{"measurements":[{"groupId":"BG000","value":"255"},{"groupId":"BG001","value":"242"},{"groupId":"BG002","value":"235"},{"groupId":"BG003","value":"732"}],"title":"Male"}],"denoms":[{"counts":[{"groupId":"BG000","value":"329"},{"groupId":"BG001","value":"328"},{"groupId":"BG002","value":"330"},{"groupId":"BG003","value":"987"}],"units":"Participants"}],"title":"All Patients"},{"categories":[{"measurements":[{"groupId":"BG000","value":"66"},{"groupId":"BG001","value":"78"},{"groupId":"BG002","value":"85"},{"groupId":"BG003","value":"229"}],"title":"Female"},{"measurements":[{"groupId":"BG000","value":"202"},{"groupId":"BG001","value":"190"},{"groupId":"BG002","value":"184"},{"groupId":"BG003","value":"576"}],"title":"Male"}],"denoms":[{"counts":[{"groupId":"BG000","value":"268"},{"groupId":"BG001","value":"268"},{"groupId":"BG002","value":"269"},{"groupId":"BG003","value":"805"}],"units":"Participants"}],"title":"Global Cohort"},{"categories":[{"measurements":[{"groupId":"BG000","value":"8"},{"groupId":"BG001","value":"9"},{"groupId":"BG002","value":"10"},{"groupId":"BG003","value":"27"}],"title":"Female"},{"measurements":[{"groupId":"BG000","value":"57"},{"groupId":"BG001","value":"52"},{"groupId":"BG002","value":"52"},{"groupId":"BG003","value":"161"}],"title":"Male"}],"denoms":[{"counts":[{"groupId":"BG000","value":"65"},{"groupId":"BG001","value":"61"},{"groupId":"BG002","value":"62"},{"groupId":"BG003","value":"188"}],"units":"Participants"}],"title":"China Cohort"}],"paramType":"COUNT_OF_PARTICIPANTS","populationDescription":"Baseline data is presented for all patients, as well as separately for the global and China cohorts.","title":"Sex: Female, Male","unitOfMeasure":"Participants"},{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","value":"7"},{"groupId":"BG001","value":"10"},{"groupId":"BG002","value":"6"},{"groupId":"BG003","value":"23"}],"title":"Hispanic or Latino"},{"measurements":[{"groupId":"BG000","value":"321"},{"groupId":"BG001","value":"315"},{"groupId":"BG002","value":"322"},{"groupId":"BG003","value":"958"}],"title":"Not Hispanic or Latino"},{"measurements":[{"groupId":"BG000","value":"1"},{"groupId":"BG001","value":"3"},{"groupId":"BG002","value":"2"},{"groupId":"BG003","value":"6"}],"title":"Unknown or Not Reported"}],"denoms":[{"counts":[{"groupId":"BG000","value":"329"},{"groupId":"BG001","value":"328"},{"groupId":"BG002","value":"330"},{"groupId":"BG003","value":"987"}],"units":"Participants"}],"title":"All Patients"},{"categories":[{"measurements":[{"groupId":"BG000","value":"7"},{"groupId":"BG001","value":"10"},{"groupId":"BG002","value":"6"},{"groupId":"BG003","value":"23"}],"title":"Hispanic or Latino"},{"measurements":[{"groupId":"BG000","value":"260"},{"groupId":"BG001","value":"255"},{"groupId":"BG002","value":"261"},{"groupId":"BG003","value":"776"}],"title":"Not Hispanic or Latino"},{"measurements":[{"groupId":"BG000","value":"1"},{"groupId":"BG001","value":"3"},{"groupId":"BG002","value":"2"},{"groupId":"BG003","value":"6"}],"title":"Unknown or Not Reported"}],"denoms":[{"counts":[{"groupId":"BG000","value":"268"},{"groupId":"BG001","value":"268"},{"groupId":"BG002","value":"269"},{"groupId":"BG003","value":"805"}],"units":"Participants"}],"title":"Global Cohort"},{"categories":[{"measurements":[{"groupId":"BG000","value":"0"},{"groupId":"BG001","value":"0"},{"groupId":"BG002","value":"0"},{"groupId":"BG003","value":"0"}],"title":"Hispanic or Latino"},{"measurements":[{"groupId":"BG000","value":"65"},{"groupId":"BG001","value":"61"},{"groupId":"BG002","value":"62"},{"groupId":"BG003","value":"188"}],"title":"Not Hispanic or Latino"},{"measurements":[{"groupId":"BG000","value":"0"},{"groupId":"BG001","value":"0"},{"groupId":"BG002","value":"0"},{"groupId":"BG003","value":"0"}],"title":"Unknown or Not Reported"}],"denoms":[{"counts":[{"groupId":"BG000","value":"65"},{"groupId":"BG001","value":"61"},{"groupId":"BG002","value":"62"},{"groupId":"BG003","value":"188"}],"units":"Participants"}],"title":"China Cohort"}],"paramType":"COUNT_OF_PARTICIPANTS","populationDescription":"Baseline data is presented for all patients, as well as separately for the global and China cohorts.","title":"Ethnicity (NIH/OMB)","unitOfMeasure":"Participants"},{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","value":"215"},{"groupId":"BG001","value":"229"},{"groupId":"BG002","value":"221"},{"groupId":"BG003","value":"665"}],"title":"White"},{"measurements":[{"groupId":"BG000","value":"1"},{"groupId":"BG001","value":"2"},{"groupId":"BG002","value":"3"},{"groupId":"BG003","value":"6"}],"title":"Black or African American"},{"measurements":[{"groupId":"BG000","value":"108"},{"groupId":"BG001","value":"96"},{"groupId":"BG002","value":"103"},{"groupId":"BG003","value":"307"}],"title":"Asian"},{"measurements":[{"groupId":"BG000","value":"5"},{"groupId":"BG001","value":"1"},{"groupId":"BG002","value":"2"},{"groupId":"BG003","value":"8"}],"title":"Other"},{"measurements":[{"groupId":"BG000","value":"0"},{"groupId":"BG001","value":"0"},{"groupId":"BG002","value":"1"},{"groupId":"BG003","value":"1"}],"title":"Missing"}],"denoms":[{"counts":[{"groupId":"BG000","value":"329"},{"groupId":"BG001","value":"328"},{"groupId":"BG002","value":"330"},{"groupId":"BG003","value":"987"}],"units":"Participants"}],"title":"All Patients"},{"categories":[{"measurements":[{"groupId":"BG000","value":"215"},{"groupId":"BG001","value":"229"},{"groupId":"BG002","value":"221"},{"groupId":"BG003","value":"665"}],"title":"White"},{"measurements":[{"groupId":"BG000","value":"1"},{"groupId":"BG001","value":"2"},{"groupId":"BG002","value":"3"},{"groupId":"BG003","value":"6"}],"title":"Black or African American"},{"measurements":[{"groupId":"BG000","value":"47"},{"groupId":"BG001","value":"36"},{"groupId":"BG002","value":"42"},{"groupId":"BG003","value":"125"}],"title":"Asian"},{"measurements":[{"groupId":"BG000","value":"5"},{"groupId":"BG001","value":"1"},{"groupId":"BG002","value":"2"},{"groupId":"BG003","value":"8"}],"title":"Other"},{"measurements":[{"groupId":"BG000","value":"0"},{"groupId":"BG001","value":"0"},{"groupId":"BG002","value":"1"},{"groupId":"BG003","value":"1"}],"title":"Missing"}],"denoms":[{"counts":[{"groupId":"BG000","value":"268"},{"groupId":"BG001","value":"268"},{"groupId":"BG002","value":"269"},{"groupId":"BG003","value":"805"}],"units":"Participants"}],"title":"Global Cohort"},{"categories":[{"measurements":[{"groupId":"BG000","value":"0"},{"groupId":"BG001","value":"0"},{"groupId":"BG002","value":"0"},{"groupId":"BG003","value":"0"}],"title":"White"},{"measurements":[{"groupId":"BG000","value":"0"},{"groupId":"BG001","value":"0"},{"groupId":"BG002","value":"0"},{"groupId":"BG003","value":"0"}],"title":"Black or African American"},{"measurements":[{"groupId":"BG000","value":"65"},{"groupId":"BG001","value":"61"},{"groupId":"BG002","value":"62"},{"groupId":"BG003","value":"188"}],"title":"Asian"},{"measurements":[{"groupId":"BG000","value":"0"},{"groupId":"BG001","value":"0"},{"groupId":"BG002","value":"0"},{"groupId":"BG003","value":"0"}],"title":"Other"},{"measurements":[{"groupId":"BG000","value":"0"},{"groupId":"BG001","value":"0"},{"groupId":"BG002","value":"0"},{"groupId":"BG003","value":"0"}],"title":"Missing"}],"denoms":[{"counts":[{"groupId":"BG000","value":"65"},{"groupId":"BG001","value":"61"},{"groupId":"BG002","value":"62"},{"groupId":"BG003","value":"188"}],"units":"Participants"}],"title":"China Cohort"}],"paramType":"COUNT_OF_PARTICIPANTS","populationDescription":"Baseline data is presented for all patients, as well as separately for the global and China cohorts.","title":"Race","unitOfMeasure":"Participants"}],"populationDescription":"Baseline analysis was based on the global full analysis set (FAS) (all patients randomized prior to the end of global recruitment) plus the China FAS (all randomized patients in the China cohort). Patients included in both cohorts are not double-counted for the baseline analysis represented by 'All Patients'."}