{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"2230","upperLimit":"9110","value":"5330"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"26"}],"units":"Participants"}],"description":"Area under the plasma concentration time curve from zero (predose) extrapolated to infinity (ng\\*h/mL) (Day 1 only), calculated by linear up/log down trapezoidal summation and extrapolated to infinity by addition of the last quantifiable concentration (Clast) divided by the apparent terminal rate constant (λz): AUC(0-last) + Clast/λz. Calculated for the C1D1 dose only.","dispersionType":"Full Range","groups":[{"description":"PK Sampling on C1D1","id":"OG000","title":"C1D1"}],"paramType":"MEDIAN","populationDescription":"PK population includes all subjects, at the selected sites in Japan and all sites in South Korea, who have pretreatment baseline and at least 1 blood sample on study providing PK data for HBI-8000.","reportingStatus":"POSTED","timeFrame":"0 (predose) up to 72 hours postdose on C1D1","title":"Pharmacokinetics AUC (0-INF)","type":"OTHER_PRE_SPECIFIED","unitOfMeasure":"ng*h/mL"}