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Folfox: Oxaliplatin 85 mg/m2 + leucovorin 400 mg/m2 + fluorouracil 400 mg/m2 IV on Day 1 of each treatment cycle, and fluorouracil 1200 mg/m2 IV continuous infusion over 24 hours (or per local standard) daily on Days 1 and 2 of each treatment cycle, every 2 weeks. This chemotherapy group consists of the two comparison chemotherapy sub-groups. Arm 2a (792 participants) is the comparison group to Arm 1 and Arm 2b (404 participants) is the comparison group to Arm 3. Some participants were counted in both Arm 2a and Arm 2b.","id":"EG001","otherNumAffected":756,"otherNumAtRisk":806,"seriousNumAffected":474,"seriousNumAtRisk":806,"title":"Chemo"},{"deathsNumAffected":361,"deathsNumAtRisk":403,"description":"1 mg/kg nivolumab administered IV over 30 minutes followed by ipilimumab 3 mg/kg administered IV over 30 minutes on Day 1 of each treatment cycle every 3 weeks for 4 doses (Cycles 1 to 4), followed by nivolumab 240 mg administered IV over 30 minutes on Day 1 of each treatment cycle every 2 weeks (Cycle 5 and beyond). Arm is closed to enrollment as of 05-June-2018.","id":"EG002","otherNumAffected":369,"otherNumAtRisk":403,"seriousNumAffected":307,"seriousNumAtRisk":403,"title":"Nivo + Ipi"}],"frequencyThreshold":"5","otherEvents":[{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Blood and lymphatic system disorders","sourceVocabulary":"24.0","stats":[{"groupId":"EG000","numAffected":312,"numAtRisk":782},{"groupId":"EG001","numAffected":276,"numAtRisk":806},{"groupId":"EG002","numAffected":132,"numAtRisk":403}],"term":"Anaemia"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Blood and lymphatic system disorders","sourceVocabulary":"24.0","stats":[{"groupId":"EG000","numAffected":75,"numAtRisk":782},{"groupId":"EG001","numAffected":64,"numAtRisk":806},{"groupId":"EG002","numAffected":9,"numAtRisk":403}],"term":"Leukopenia"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Blood and lymphatic system 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Serious Adverse events and other adverse events were assessed from date of first dose to 100 days following date of last dose (up to approximately 5 years)."}