{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","value":"1.27"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"6"}],"units":"Participants"}],"description":"Half-life (t½): terminal half-life\n\nThe mean apparent t½ following instillation of mitomycin into the upper urinary tract (UUT) was 1.27 hours (76 minutes), which was longer than the true t½ of mitomycin following a 30 mg bolus injection (mean t½ value of approximately 17 minutes). The apparent t½ demonstrates that UGN-101 dissolved gradually, resulting in prolonged exposure of mitomycin following local instillation into the UUT.","groups":[{"description":"The PK profiles of the first UGN-101 instillation in the blood were to be examined for the first 6 patients.","id":"OG000","title":"Pharmacokinetic Population"}],"paramType":"NUMBER","populationDescription":"PK Analysis Set: Consisted of patients who signed consent for PK and had sufficient PK data for the determination of PK parameters.","reportingStatus":"POSTED","timeFrame":"Blood samples were collected at 0 minutes (pre-dose) and 30 minutes, 1, 2, 3, 4, 5, and 6 hours following the first instillation with UGN-101","title":"Pharmacokinetic: The PK Profiles of the First UGN-101 Instillation in the Blood Were to be Examined for the First 6 Patients.","type":"SECONDARY","unitOfMeasure":"Hours"}