{"classes":[{"categories":[{"measurements":[{"groupId":"OG003","lowerLimit":"8.1","upperLimit":"41.1","value":"24.64"},{"groupId":"OG005","lowerLimit":"8.14","upperLimit":"8.14","value":"8.14"},{"groupId":"OG006","lowerLimit":"5.7","upperLimit":"8.1","value":"7.86"},{"groupId":"OG007","lowerLimit":"56.0","upperLimit":"56.0","value":"56.0"},{"groupId":"OG008","lowerLimit":"8.14","upperLimit":"8.14","value":"8.14"},{"groupId":"OG009","lowerLimit":"10.1","upperLimit":"56.1","value":"33.14"},{"groupId":"OG010","lowerLimit":"4.1","upperLimit":"8.3","value":"4.14"},{"groupId":"OG011","lowerLimit":"4.1","upperLimit":"16.1","value":"7.14"},{"groupId":"OG012","lowerLimit":"4.1","upperLimit":"20.1","value":"12.14"},{"groupId":"OG013","lowerLimit":"8.4","upperLimit":"12.0","value":"10.21"},{"groupId":"OG014","lowerLimit":"4.1","upperLimit":"20.4","value":"8.14"},{"groupId":"OG015","lowerLimit":"4.3","upperLimit":"12.1","value":"8.07"},{"groupId":"OG016","lowerLimit":"3.9","upperLimit":"19.9","value":"4.21"},{"groupId":"OG018","lowerLimit":"4.14","upperLimit":"4.14","value":"4.14"},{"groupId":"OG019","lowerLimit":"7.86","upperLimit":"7.86","value":"7.86"},{"groupId":"OG020","lowerLimit":"4.1","upperLimit":"12.0","value":"4.14"},{"groupId":"OG021","lowerLimit":"4.0","upperLimit":"13.1","value":"4.14"},{"groupId":"OG022","lowerLimit":"6.14","upperLimit":"6.14","value":"6.14"},{"groupId":"OG023","lowerLimit":"3.1","upperLimit":"13.1","value":"3.14"},{"groupId":"OG024","lowerLimit":"3.1","upperLimit":"9.1","value":"3.71"},{"groupId":"OG025","lowerLimit":"3.0","upperLimit":"7.3","value":"3.36"},{"groupId":"OG026","lowerLimit":"4.1","upperLimit":"8.1","value":"4.14"},{"groupId":"OG027","lowerLimit":"4.0","upperLimit":"62.1","value":"8.14"},{"groupId":"OG028","lowerLimit":"4.1","upperLimit":"11.1","value":"8.86"},{"groupId":"OG029","lowerLimit":"4.1","upperLimit":"8.3","value":"6.14"},{"groupId":"OG030","lowerLimit":"4.14","upperLimit":"4.14","value":"4.14"},{"groupId":"OG031","lowerLimit":"4.1","upperLimit":"23.3","value":"6.29"},{"groupId":"OG032","lowerLimit":"3.14","upperLimit":"3.14","value":"3.14"},{"groupId":"OG033","lowerLimit":"3.0","upperLimit":"17.0","value":"3.14"},{"groupId":"OG034","lowerLimit":"4.0","upperLimit":"49.0","value":"5.07"},{"groupId":"OG035","lowerLimit":"4.0","upperLimit":"25.1","value":"4.14"},{"groupId":"OG036","lowerLimit":"4.0","upperLimit":"9.3","value":"4.14"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"0"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"2"},{"groupId":"OG004","value":"0"},{"groupId":"OG005","value":"1"},{"groupId":"OG006","value":"3"},{"groupId":"OG007","value":"1"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"2"},{"groupId":"OG010","value":"4"},{"groupId":"OG011","value":"3"},{"groupId":"OG012","value":"2"},{"groupId":"OG013","value":"2"},{"groupId":"OG014","value":"7"},{"groupId":"OG015","value":"4"},{"groupId":"OG016","value":"28"},{"groupId":"OG017","value":"0"},{"groupId":"OG018","value":"1"},{"groupId":"OG019","value":"1"},{"groupId":"OG020","value":"8"},{"groupId":"OG021","value":"14"},{"groupId":"OG022","value":"1"},{"groupId":"OG023","value":"3"},{"groupId":"OG024","value":"7"},{"groupId":"OG025","value":"6"},{"groupId":"OG026","value":"3"},{"groupId":"OG027","value":"4"},{"groupId":"OG028","value":"3"},{"groupId":"OG029","value":"4"},{"groupId":"OG030","value":"1"},{"groupId":"OG031","value":"14"},{"groupId":"OG032","value":"1"},{"groupId":"OG033","value":"15"},{"groupId":"OG034","value":"24"},{"groupId":"OG035","value":"25"},{"groupId":"OG036","value":"22"}],"units":"Participants"}],"description":"Time to response is defined as the time from the first dose date of study treatment to the first date of documented response (PR or better).\n\nTime to response will be summarized for responders using descriptive statistics by cohort and dose level.","dispersionType":"Full Range","groups":[{"description":"CC220 0.30mg","id":"OG000","title":"Cohort A: Treatment 1"},{"description":"CC220 0.45mg","id":"OG001","title":"Cohort A: Treatment 2"},{"description":"CC220 0.60mg","id":"OG002","title":"Cohort A: Treatment 3"},{"description":"CC220 0.75mg","id":"OG003","title":"Cohort A: Treatment 4"},{"description":"CC220 0.90mg","id":"OG004","title":"Cohort A: Treatment 5"},{"description":"CC220 1.0mg","id":"OG005","title":"Cohort A: Treatment 6"},{"description":"CC220 0.30mg + DEX","id":"OG006","title":"Cohort B: Treatment 1"},{"description":"CC220 0.45mg + DEX","id":"OG007","title":"Cohort B: Treatment 2"},{"description":"CC220 0.60mg + DEX","id":"OG008","title":"Cohort B: Treatment 3"},{"description":"CC220 0.75mg + DEX","id":"OG009","title":"Cohort B: Treatment 4"},{"description":"CC220 0.90mg + DEX","id":"OG010","title":"Cohort B: Treatment 5"},{"description":"CC220 1.0mg + DEX","id":"OG011","title":"Cohort B: Treatment 6"},{"description":"CC220 1.1mg + DEX","id":"OG012","title":"Cohort B: Treatment 7"},{"description":"CC220 1.2mg + DEX","id":"OG013","title":"Cohort B: Treatment 8"},{"description":"CC220 1.3.mg + DEX","id":"OG014","title":"Cohort B: Treatment 9"},{"description":"CC220 1.6mg + DEX","id":"OG015","title":"Cohort B: Treatment 10"},{"description":"CC220 + DEX","id":"OG016","title":"Cohort D: Treatment 1"},{"description":"CC220 1.0mg + DARA + DEX","id":"OG017","title":"Cohort E: Treatment 1"},{"description":"CC220 1.1mg + DARA + DEX","id":"OG018","title":"Cohort E: Treatment 2"},{"description":"CC220 1.2mg + DARA + DEX","id":"OG019","title":"Cohort E: Treatment 3"},{"description":"CC220 1.3mg + DARA + DEX","id":"OG020","title":"Cohort E: Treatment 4"},{"description":"CC220 1.6mg + DARA + DEX","id":"OG021","title":"Cohort E: Treatment 5"},{"description":"CC220 1.0mg + BORT + DEX","id":"OG022","title":"Cohort F: Treatment 1"},{"description":"CC220 1.1mg + BORT + DEX","id":"OG023","title":"Cohort F: Treatment 2"},{"description":"CC220 1.3mg + BORT + DEX","id":"OG024","title":"Cohort F: Treatment 3"},{"description":"CC220 1.6mg + BORT + DEX","id":"OG025","title":"Cohort F: Treatment 4"},{"description":"CC220 1.1mg + CFZ + DEX","id":"OG026","title":"Cohort G: Treatment 1"},{"description":"CC220 1.3mg + CFZ + DEX","id":"OG027","title":"Cohort G: Treatment 2"},{"description":"CC220 1.6mg + CFZ + DEX","id":"OG028","title":"Cohort G: Treatment 3"},{"description":"CC220 + DEX","id":"OG029","title":"Cohort H1"},{"description":"CC220 + DEX","id":"OG030","title":"Cohort H2"},{"description":"CC220 + DEX","id":"OG031","title":"Cohort I"},{"description":"CC220Vd 1.0mg + NE-ASCT","id":"OG032","title":"Cohort J1: Treatment 1"},{"description":"CC220Vd 1.6mg + NE-ASCT","id":"OG033","title":"Cohort J1: Treatment 2"},{"description":"CC220 1.0mg + DARA + DEX","id":"OG034","title":"Cohort K: Treatment 1"},{"description":"CC220 1.3mg + DARA + DEX","id":"OG035","title":"Cohort K: Treatment 2"},{"description":"CC220 1.6mg + DARA + DEX","id":"OG036","title":"Cohort K: Treatment 3"}],"paramType":"MEDIAN","populationDescription":"Safety Population - Responders Only","reportingStatus":"POSTED","timeFrame":"On Average of (Cohort A:19.14, Cohort B: 12.39, Cohort D: 7.54, Cohort E: 5.44, Cohort F: 4.97, Cohort G: 12.30, Cohort H: 4.14, Cohort I: 8.79, Cohort J: 4.76, Cohort K: 6.51) Weeks","title":"Time to Response (TTR)","type":"SECONDARY","unitOfMeasure":"Weeks"}