{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"0.0","upperLimit":"70.8","value":"0"},{"groupId":"OG001","lowerLimit":"0.0","upperLimit":"70.8","value":"0"},{"groupId":"OG002","lowerLimit":"0.0","upperLimit":"60.2","value":"0"},{"groupId":"OG003","lowerLimit":"4.3","upperLimit":"77.7","value":"33.3"},{"groupId":"OG004","lowerLimit":"0.0","upperLimit":"45.9","value":"0"},{"groupId":"OG005","lowerLimit":"0.4","upperLimit":"57.9","value":"14.3"},{"groupId":"OG006","lowerLimit":"6.7","upperLimit":"65.2","value":"30.0"},{"groupId":"OG007","lowerLimit":"0.8","upperLimit":"90.6","value":"33.3"},{"groupId":"OG008","lowerLimit":"0.8","upperLimit":"90.6","value":"33.3"},{"groupId":"OG009","lowerLimit":"9.4","upperLimit":"99.2","value":"66.7"},{"groupId":"OG010","lowerLimit":"9.1","upperLimit":"61.4","value":"30.8"},{"groupId":"OG011","lowerLimit":"5.0","upperLimit":"53.8","value":"23.1"},{"groupId":"OG012","lowerLimit":"2.5","upperLimit":"55.6","value":"20.0"},{"groupId":"OG013","lowerLimit":"3.2","upperLimit":"65.1","value":"25.0"},{"groupId":"OG014","lowerLimit":"23.0","upperLimit":"77.0","value":"50.0"},{"groupId":"OG015","lowerLimit":"9.1","upperLimit":"61.4","value":"30.8"},{"groupId":"OG016","lowerLimit":"18.1","upperLimit":"35.6","value":"26.2"},{"groupId":"OG017","lowerLimit":"0.0","upperLimit":"70.8","value":"0"},{"groupId":"OG018","lowerLimit":"0.8","upperLimit":"90.6","value":"33.3"},{"groupId":"OG019","lowerLimit":"0.5","upperLimit":"71.6","value":"20.0"},{"groupId":"OG020","lowerLimit":"31.6","upperLimit":"86.1","value":"61.5"},{"groupId":"OG021","lowerLimit":"33.4","upperLimit":"73.4","value":"53.8"},{"groupId":"OG022","lowerLimit":"0.8","upperLimit":"90.6","value":"33.3"},{"groupId":"OG023","lowerLimit":"9.9","upperLimit":"81.6","value":"42.9"},{"groupId":"OG024","lowerLimit":"34.8","upperLimit":"93.3","value":"70.0"},{"groupId":"OG025","lowerLimit":"29.9","upperLimit":"92.5","value":"66.7"},{"groupId":"OG026","lowerLimit":"19.4","upperLimit":"99.4","value":"75.0"},{"groupId":"OG027","lowerLimit":"15.7","upperLimit":"84.3","value":"50.0"},{"groupId":"OG028","lowerLimit":"19.4","upperLimit":"99.4","value":"75.0"},{"groupId":"OG029","lowerLimit":"22.3","upperLimit":"95.7","value":"66.7"},{"groupId":"OG030","lowerLimit":"0.5","upperLimit":"71.6","value":"20.0"},{"groupId":"OG031","lowerLimit":"20.1","upperLimit":"50.6","value":"34.1"},{"groupId":"OG032","lowerLimit":"2.5","upperLimit":"100.0","value":"100.0"},{"groupId":"OG033","lowerLimit":"56.6","upperLimit":"96.2","value":"82.4"},{"groupId":"OG034","lowerLimit":"79.6","upperLimit":"99.9","value":"96.0"},{"groupId":"OG035","lowerLimit":"86.3","upperLimit":"100.0","value":"100.0"},{"groupId":"OG036","lowerLimit":"68.8","upperLimit":"97.5","value":"88.0"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"3"},{"groupId":"OG001","value":"3"},{"groupId":"OG002","value":"4"},{"groupId":"OG003","value":"6"},{"groupId":"OG004","value":"6"},{"groupId":"OG005","value":"7"},{"groupId":"OG006","value":"10"},{"groupId":"OG007","value":"3"},{"groupId":"OG008","value":"3"},{"groupId":"OG009","value":"3"},{"groupId":"OG010","value":"13"},{"groupId":"OG011","value":"13"},{"groupId":"OG012","value":"10"},{"groupId":"OG013","value":"8"},{"groupId":"OG014","value":"14"},{"groupId":"OG015","value":"13"},{"groupId":"OG016","value":"107"},{"groupId":"OG017","value":"3"},{"groupId":"OG018","value":"3"},{"groupId":"OG019","value":"5"},{"groupId":"OG020","value":"13"},{"groupId":"OG021","value":"26"},{"groupId":"OG022","value":"3"},{"groupId":"OG023","value":"7"},{"groupId":"OG024","value":"10"},{"groupId":"OG025","value":"9"},{"groupId":"OG026","value":"4"},{"groupId":"OG027","value":"8"},{"groupId":"OG028","value":"4"},{"groupId":"OG029","value":"6"},{"groupId":"OG030","value":"5"},{"groupId":"OG031","value":"41"},{"groupId":"OG032","value":"1"},{"groupId":"OG033","value":"17"},{"groupId":"OG034","value":"25"},{"groupId":"OG035","value":"25"},{"groupId":"OG036","value":"25"}],"units":"Participants"}],"description":"Tumor response, including progressive disease (PD) according to the IMWG Uniform Response Criteria (Kumar, 2016) for subjects who achieved partial response (PR) or better.","dispersionType":"95% Confidence Interval","groups":[{"description":"CC220 0.30mg","id":"OG000","title":"Cohort A: Treatment 1"},{"description":"CC220 0.45mg","id":"OG001","title":"Cohort A: Treatment 2"},{"description":"CC220 0.60mg","id":"OG002","title":"Cohort A: Treatment 3"},{"description":"CC220 0.75mg","id":"OG003","title":"Cohort A: Treatment 4"},{"description":"CC220 0.90mg","id":"OG004","title":"Cohort A: Treatment 5"},{"description":"CC220 1.0mg","id":"OG005","title":"Cohort A: Treatment 6"},{"description":"CC220 0.30mg + DEX","id":"OG006","title":"Cohort B: Treatment 1"},{"description":"CC220 0.45mg + DEX","id":"OG007","title":"Cohort B: Treatment 2"},{"description":"CC220 0.60mg + DEX","id":"OG008","title":"Cohort B: Treatment 3"},{"description":"CC220 0.75mg + DEX","id":"OG009","title":"Cohort B: Treatment 4"},{"description":"CC220 0.90mg + DEX","id":"OG010","title":"Cohort B: Treatment 5"},{"description":"CC220 1.0mg + DEX","id":"OG011","title":"Cohort B: Treatment 6"},{"description":"CC220 1.1mg + DEX","id":"OG012","title":"Cohort B: Treatment 7"},{"description":"CC220 1.2mg + DEX","id":"OG013","title":"Cohort B: Treatment 8"},{"description":"CC220 1.3.mg + DEX","id":"OG014","title":"Cohort B: Treatment 9"},{"description":"CC220 1.6mg + DEX","id":"OG015","title":"Cohort B: Treatment 10"},{"description":"CC220 + DEX","id":"OG016","title":"Cohort D: Treatment 1"},{"description":"CC220 1.0mg + DARA + DEX","id":"OG017","title":"Cohort E: Treatment 1"},{"description":"CC220 1.1mg + DARA + DEX","id":"OG018","title":"Cohort E: Treatment 2"},{"description":"CC220 1.2mg + DARA + DEX","id":"OG019","title":"Cohort E: Treatment 3"},{"description":"CC220 1.3mg + DARA + DEX","id":"OG020","title":"Cohort E: Treatment 4"},{"description":"CC220 1.6mg + DARA + DEX","id":"OG021","title":"Cohort E: Treatment 5"},{"description":"CC220 1.0mg + BORT + DEX","id":"OG022","title":"Cohort F: Treatment 1"},{"description":"CC220 1.1mg + BORT + DEX","id":"OG023","title":"Cohort F: Treatment 2"},{"description":"CC220 1.3mg + BORT + DEX","id":"OG024","title":"Cohort F: Treatment 3"},{"description":"CC220 1.6mg + BORT + DEX","id":"OG025","title":"Cohort F: Treatment 4"},{"description":"CC220 1.1mg + CFZ + DEX","id":"OG026","title":"Cohort G: Treatment 1"},{"description":"CC220 1.3mg + CFZ + DEX","id":"OG027","title":"Cohort G: Treatment 2"},{"description":"CC220 1.6mg + CFZ + DEX","id":"OG028","title":"Cohort G: Treatment 3"},{"description":"CC220 + DEX","id":"OG029","title":"Cohort H1"},{"description":"CC220 + DEX","id":"OG030","title":"Cohort H2"},{"description":"CC220 + DEX","id":"OG031","title":"Cohort I"},{"description":"CC220Vd 1.0mg + NE-ASCT","id":"OG032","title":"Cohort J1: Treatment 1"},{"description":"CC220Vd 1.6mg + NE-ASCT","id":"OG033","title":"Cohort J1: Treatment 2"},{"description":"CC220 1.0mg + DARA + DEX","id":"OG034","title":"Cohort K: Treatment 1"},{"description":"CC220 1.3mg + DARA + DEX","id":"OG035","title":"Cohort K: Treatment 2"},{"description":"CC220 1.6mg + DARA + DEX","id":"OG036","title":"Cohort K: Treatment 3"}],"paramType":"NUMBER","populationDescription":"Safety Population","reportingStatus":"POSTED","timeFrame":"On Average of (Cohort A: 44.96, Cohort B: 32.79, Cohort D: 21.14, Cohort E: 53.74, Cohort F: 46.34, Cohort G: 63.26, Cohort H1: 58.10, Cohort H2: 22.11, Cohort I: 20.96, Cohort J: 86.21, Cohort K: 56.29) Weeks","title":"Overall Response Rate (ORR)","type":"SECONDARY","unitOfMeasure":"Percentage of Participants"}