{"analyses":[{"ciLowerLimit":"-0141","ciNumSides":"TWO_SIDED","ciPctValue":"95","ciUpperLimit":"-0.024","dispersionType":"STANDARD_ERROR_OF_MEAN","dispersionValue":"0.03","groupIds":["OG000","OG001"],"nonInferiorityType":"OTHER","pValue":"0.01","paramType":"Slope","paramValue":"-0,083","statisticalComment":"The treatment effect was determined by testing the significance of the group by time interaction in GEE using a one degree-of-freedom (df) test.","statisticalMethod":"Generalized Estimating Equation (GEE)"}],"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.0501","value":"4.5836"},{"groupId":"OG001","spread":"0.0565","value":"4.5269"}]}],"title":"BL"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.0431","value":"4.6035"},{"groupId":"OG001","spread":"0.0463","value":"4.565"}]}],"title":"6m"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.0556","value":"4.636"},{"groupId":"OG001","spread":"0.0768","value":"4.5884"}]}],"title":"12m"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.0568","value":"4.6032"},{"groupId":"OG001","spread":"0.0663","value":"4.5462"}]}],"title":"18m"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.0614","value":"4.5147"},{"groupId":"OG001","spread":"0.067","value":"4.5976"}]}],"title":"24"}],"denoms":[{"counts":[{"groupId":"OG000","value":"75"},{"groupId":"OG001","value":"76"}],"units":"Participants"}],"description":"Thickness of cardiac muscle (in cm) of the left ventricle at the end of diastole. The mean is reported by arm at each timepoint with corresponding standard errors.","dispersionType":"Standard Error","groups":[{"description":"Patients received Carvedilol PO delivered at 6.25 mg twice daily (for a total dose of 12.5 mg per day) for 24 months.","id":"OG000","title":"Arm I (Carvedilol)"},{"description":"Patients received Carvedilol PO delivered at 6.25 mg twice daily (for a total dose of 12.5 mg per day) for 24 months.","id":"OG001","title":"Arm II (Placebo)"}],"paramType":"MEAN","populationDescription":"We excluded 31 participants who did not have a second time point assessment of echocardiography, resulting in 151 analyzable participants.","reportingStatus":"POSTED","timeFrame":"Baseline before treatment, 6 months, 12 months, 18 months, 24 months after treatment initiation","title":"Average Left Ventricular End-diastolic Dimension","type":"SECONDARY","unitOfMeasure":"cm"}