{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"1.00","upperLimit":"24.00","value":"2.00"},{"groupId":"OG001","lowerLimit":"0.50","upperLimit":"8.00","value":"2"},{"groupId":"OG002","lowerLimit":"2.00","upperLimit":"4.00","value":"2.00"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"12"},{"groupId":"OG001","value":"99"},{"groupId":"OG002","value":"7"}],"units":"Participants"}],"title":"C1D1"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"1.00","upperLimit":"4.00","value":"1.00"},{"groupId":"OG001","lowerLimit":"0.50","upperLimit":"8.00","value":"2"},{"groupId":"OG002","lowerLimit":"2.00","upperLimit":"4.00","value":"2.00"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"10"},{"groupId":"OG001","value":"89"},{"groupId":"OG002","value":"7"}],"units":"Participants"}],"title":"C1D8"}],"denoms":[{"counts":[{"groupId":"OG000","value":"12"},{"groupId":"OG001","value":"99"},{"groupId":"OG002","value":"7"}],"units":"Participants"}],"description":"Time to maximum plasma concentration of INCB057643 administered as monotherapy in fasted state","dispersionType":"Full Range","groups":[{"description":"Initial cohort dose of INCB057643 monotherapy at the protocol specified starting dose in the Part 1 TGA,TGB,TGC, and Part 2 TGA","id":"OG000","title":"8mg QD INCB057643"},{"description":"Initial cohort dose of INCB057643 monotherapy at the protocol specified starting dose in the Part 1 TGA,TGB, and Part 2 TGA","id":"OG001","title":"12mg QD INCB057643"},{"description":"Initial cohort dose of INCB057643 monotherapy at the protocol specified starting dose in the Part 1 TGA","id":"OG002","title":"16mg QD INCB057643"}],"paramType":"MEDIAN","populationDescription":"PK evaluable population includes all subjects who received at least 1 dose of study drug and had at least 1 PK sample collected and analyzed","reportingStatus":"POSTED","timeFrame":"Predose, 0.5, 1, 2, 4, 6, 8 hours on C1D1 and C1D8","title":"Tmax: Time to Maximum Plasma Concentration of INCB057643","type":"SECONDARY","unitOfMeasure":"hours"}