{"calculatePct":false,"classes":[{"categories":[{"measurements":[{"groupId":"OG000","value":"51"},{"groupId":"OG001","value":"50"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"51"},{"groupId":"OG001","value":"50"}],"units":"Participants"}],"description":"Estimate the proportion of subjects who have a successful collection of stem cells (\\> 2 million Cluster of Differentiation 34 (CD34) cells/Kg of body weight) for autologous transplant in both treatment groups.","groups":[{"description":"Standard of Care Stem cell collection without in-vivo purging with Bortezomib. Standard of Care drugs Granulocyte colony-stimulating factor (G-CSF) +/- Mozobil (the latter if needed).\n\nNOTE: Multiparametric Flow Cytometry to be performed on samples for BOTH groups A and B\n\nGranulocyte colony-stimulating factor (G-CSF): Granulocyte colony-stimulating factor (G-CSF) will be given to all participants by injection under the skin 4 days and 1 day before stem cell collection, and then continued until the stem cell collection is completed.\n\nMozobil: Mozobil will be given to all participants by injection under the skin only if needed per Investigator.","id":"OG000","title":"Stem Cell Collection Without In-vivo Purging With Bortezomib"},{"description":"Bortezomib will be given subcutaneously (SQ) at 1.3 mg/m2 on day -11 and day -8 followed by Granulocyte colony-stimulating factor (G-CSF) given SQ on day -4 thru day -1 and continued until the collection is completed. Mozobil will be given if needed.\n\nThere must be at least 72 hours between each dose of bortezomib. NOTE: Multiparametric Flow Cytometry to be performed on samples for BOTH groups A and B\n\nBortezomib: Bortezomib will be given to Group B participants by injection under the skin 11 days and 8 days before stem cell collection.\n\nGranulocyte colony-stimulating factor (G-CSF): Granulocyte colony-stimulating factor (G-CSF) will be given to all participants by injection under the skin 4 days and 1 day before stem cell collection, and then continued until the stem cell collection is completed.\n\nMozobil: Mozobil will be given to all participants by injection under the skin only if needed per Investigator.","id":"OG001","title":"Stem Cell Collection With In-vivo Purging With Bortezomib"}],"paramType":"COUNT_OF_PARTICIPANTS","reportingStatus":"POSTED","timeFrame":"Within the first 30 days after stem cell collection","title":"Multiparametric Flow Cytometry - Cluster of Differentiation 34 (CD34)Assessment","type":"SECONDARY","unitOfMeasure":"Participants"}